SAMA HOOLE: Mushrooms have significant issues: Contain chitin (humans can't digest) High in purines (gout trigger) Accumulate heavy metals from soil

Mushrooms have significant issues:

Contain chitin (humans can't digest)
High in purines (gout trigger)
Accumulate heavy metals from soil
Many are toxic without cooking
Nutritional value is minimal

They're fungus, not food.

— Sama Hoole (@SamaHoole) October 4, 2025

I have recommended Lion's Mane and other mushrooms before.  And I sure have enjoyed sauteed mushrooms before I learned of their questionable nutritional value. 

SAMA HOOLE: Day 5 of carnivore: "This isn't working, I feel awful." You spent 30 years running on glucose. Your mitochondria need at least 4-6 weeks to upregulate fat oxidation enzymes. You're quitting during the adaptation phase.

Day 5 of carnivore: "This isn't working, I feel awful."

You spent 30 years running on glucose.

Your mitochondria need at least 4-6 weeks to upregulate fat oxidation enzymes.

You're quitting during the adaptation phase.

That's like canceling your gym membership on day 3…

— Sama Hoole (@SamaHoole) October 4, 2025