SAMA HOOLE: Mushrooms have significant issues: Contain chitin (humans can't digest) High in purines (gout trigger) Accumulate heavy metals from soil

Mushrooms have significant issues:

Contain chitin (humans can't digest)
High in purines (gout trigger)
Accumulate heavy metals from soil
Many are toxic without cooking
Nutritional value is minimal

They're fungus, not food.

— Sama Hoole (@SamaHoole) October 4, 2025

I have recommended Lion's Mane and other mushrooms before.  And I sure have enjoyed sauteed mushrooms before I learned of their questionable nutritional value. 

MUSHROOMS. WHO KNEW?

Positive mental psychological states are associated with longer telomeres, whereas negative psychological conditions (e.g. chronic stress, anxiety, and depression) are associated with telomere attrition.  --Kato, Kleinhenz, et al

Decentralize medicine.
Learn to grow your meds. https://t.co/qDLQ8lnlM9

— Kevin McKernan (@Kevin_McKernan) July 10, 2025

Beta Glucans.

Mesima.

Lion's Mane, et al.

“We provide the first experimental evidence that psilocin (the active metabolite of psilocybin) treatment extends cellular lifespan and psilocybin treatment promotes increased longevity in aged mice, suggesting that psilocybin may be a potent gero-protective agent.”

https://www.nature.com/articles/s41514-025-00244-x.

Human studies have demonstrated that a single-dose of psilocybin can improve debilitating physical and psychological symptoms—with durable effects (up to ~5 years)

Despite considerable clinical evidence supporting the therapeutic benefits of psilocybin, the molecular mechanisms responsible for these impacts remain enigmatic. Studies with psilocybin have predominantly focused on neurological impacts and/or behavioral outcomes; few studies have evaluated alternative or systemic mechanisms which may also contribute to its beneficial effects. The “psilocybin-telomere hypothesis”6 postulates that psilocybin interventions may quantifiably impact telomere length, which offers a potential explanation for its efficacy across a wide range of clinical indications. This hypothesis is based on a large corpus of studies linking mental health biological aging markers.  Accumulating evidence indicate that clinical depression accelerates aging and telomere shortening. Positive mental psychological states are associated with longer telomeres, whereas negative psychological conditions (e.g. chronic stress, anxiety, and depression) are associated with telomere attrition. Given the clinical evidence supporting the efficacy of psilocybin for these conditions, it is plausible that psilocybin may impact telomere length. However, no prior studies have experimentally investigated the direct impact of psilocybin on biological aging.

IP6 & mushrooms for the win, ONCE AGAIN! Pancreatic Cancer Gone.

IP6 & mushrooms for the win, ONCE AGAIN!

Pancreatic Cancer Gone.

A small amt of Fenben was used, too.

(This is from a lady in my FB group. The cancer has been GONE 4 yrs now. 😯)

They should just change the labels on IP6 & mushroom bottles to: Fuck Cancer. pic.twitter.com/lCuHvNTtVK

— Natural Immunity FTW (@NaturallyFTW) March 22, 2024

Mushrooms Slow Down Premature Aging Effect

Vitamin E removes the build-up of hydrogen peroxide overload in the body.  Fights against premature wrinkles.  It improves the skin.  The pituitary is storage for a lot of vitamin E, so when you go into menopause and you lose the function of the ovaries because you're not going to have babies anymore, guess what happens?  Your vitamin E drops dramatically.  Premenopausal women have much lower vitamin E levels than they did before that change.  

Maybe deficient in B vitamins because the microbiome of your gut isn't recycling these B vitamins.  I supplement with Biotin which makes my hair thicker, which is nice, but it doesn't do a thing for hair color.  Biotin is a good antidote for alopecia that many experienced from COVID or from the injection.  

The goal here then is to increase the good bacteria in the gut, but how does one do that?  Dr. Berg ends with saying, "Take a really good probiotic."  Well, which one?  

Okay, still no answer as of yet on which is the best probiotic.  In the meantime, he does offer some nutritional compounds that help to prevent graying.  Imagine my surprise when PABA, or B5, was not mentioned.  He lists: 

1.  Catalase, an enzyme that helps breakdown hydrogen peroxide.

2.  Glutathione, the master antioxidant that helps reduce hydrogen peroxide.

3.  Selenium, an antioxidant.

4.  Coconut Oil.  Put this on your scalp, get it into the pours.

FOR THEIR LACK OF KNOWLEDGE, THE PEOPLE PERISH

This was a decent presentation, meaning that it took a complex topic and made it comprehensible. It did fail, however, to answer how to balance gut microbes so that you restore your body and your health returns to a more normal state.  Dr. Sears' Zone Diet focused on balancing hormones.  His diet plan definitely does that, for sure.  And as a target, balancing hormones is a good one.  But maybe balancing the whole body is not as easily as we think since certain organs and organ systems, due to their size and volume, play a larger role in health maintenance than others.  The gut is large system.  In fact, the gut starts at your mouth.  Never heard that before.  

The gut (gastrointestinal tract) is the long tube that starts at the mouth and ends at the back passage (anus).  

The key is to know how to repair and remedy a leaky gut. A leaky gut is exactly what it sounds like--it means your gut is porous with all kinds of bacteria spilling out gradually perhaps into other compartments of your body.  That's a large area, so let's be specific.  A leaky gut refers mainly to the small intestine.  You may not even feel any specific pain other than a tire or weak stomach. Or it may show up in the form of dry or flaky skin. It may show up in the form of bruises or scarring.  

CAUSES OF LEAKY GUT  
The list is long.  One thing that tops the causes of a leaky gut is a poor diet.  What does that mean?  We're all guilty of that.  Even if one follows the best diet, we're always tinkering with so as to accommodate our preferences, little cravings, and must-haves.  Eating all vegetables is not good enough.  Prebiotics are perhaps the best foods to eat to restore the gut.  See this list:

Low-fat diets that never satisfy and only induce more food craving instead of a varietal diet rich in prebiotics like mushrooms, pickles, sauerkraut, miso soup, bran, oats, barley that populate our gut with bacteria that produces lean, non-diabetic humans.

At another site, Sardi points out how unhealthy bacteria, the kind that causes your intestines to leak, produces inflammation at the back of your eyes and is responsible for macular degeneration.  Healthy gut bacteria inhibits invasive blood vessels that destroy vision.  

Healthy gut bacteria inhibit inflammation.  Unhealthy gut bacteria generates low-grade inflammation that is characteristic of accelerated ageing.

Fermented foods like pickles, sauerkraut, miso soup, apple pectin, beta glucans (barley), resveratrol and other foods are recommended to restore and maintain healthy gut bacteria.

Unhealthy gut bacteria increase intestinal permeability and allow undigested proteins to enter the blood circulation, sparking allergic and autoimmune reactions.  [EMBO Molecular Medicine Oct 11, 2016]

This explains how fermented and prebiotic foods listed above spare your vision, spare your gut health, spare your immune system.  And how the Biblical saying of "For their lack of knowledge, the people perish" is no small statement.  The gut and its healthy and unhealthy bacteria is a complex topic.  Though the solutions have already been discovered.  We know what works--prebiotics.  Dairy prebiotics may not be the best.  On probiotics versus prebiotics, this might be helpful.  



Probiotics are “good” bacteria that help keep your digestive system healthy by controlling growth of harmful bacteria. Prebiotics are carbohydrates that cannot be digested by the human body. They are food for probiotics. The primary benefit of probiotics and prebiotics appears to be helping you maintain a healthy digestive system.

One of the best sources of probiotics is yogurt. It has good bacteria like lactobacillus or bifidobacteria. Look for “live or active cultures” on the label to be sure your favorite brand of yogurt is a rich source of probiotics. Other good food sources are sauerkraut, miso soup, fermented, soft cheeses (like Gouda), and even sourdough bread. The common feature of all these foods is fermentation, a process that produces probiotics.

There is nothing in particular about probiotics or prebiotics that will give you energy. However, one of the best probiotic-rich foods, yogurt, is an excellent source of lean protein and calcium. Prebiotic foods are a great source of vitamins, minerals, and other nutrients that give you the energy you need to get through the day. Prebiotic-rich foods include whole grains, onions, bananas, garlic, honey, and artichokes.

SERIOUS PROBLEMS FROM A LEAKY GUT  

One of the problems with diagnosing conditions and knowing what you're working with is that the symptoms show up in distal points and start as something else.  Bill Sardi points this out elegantly

Some autoimmune conditions start as something else. Take, for example, Lyme disease. An infection (Borrelia burgdorferi) may or may not result from a tick bite. Such an infection may or may not be quelled by antibiotics. If people are low in zinc, the medication is less likely to be effective. If they are low in critical nutrients and/or have an imbalance in gut bacteria, they be more prone to autoimmune reactions.  So, seemingly out of nowhere, an infection from a tick bite mysteriously becomes an unremitting chronic problem. That effect is reported more frequently among those who are zinc-deficient. Tick bites and the infections have been around throughout human history. The new element may be zinc deficiency made worse by a craving for sugar that is too often satisfied with high fructose corn syrup. 

So in addition to those fermented probiotics, like miso soup, sauerkraut, mushrooms, and others, you need to be on zinc.  The best form of Zinc is OptiZinc.  Bill Sardi explains that high-fructose corn syrup depletes zinc.  We really need to be careful of the sweeteners we're consuming.  

Zinc is crucial for proper function of the immune system (and so much more). Zinc deficiency is rampant in the American population. Anyone who doesn’t get enough zinc or can’t use it properly is prone to autoimmune reactions. It is possible to get enough zinc in the diet, but it takes adequate selenium to release the zinc from its binding protein. And you should know that high fructose corn syrup (HFCS) depletes zinc. Given the high consumption of HFCS in the US, the increasing incidence of autoimmune disorders is not surprising. 

So there's that.

BEWARE OF HOSPITALIZED ANTIOBIOTICS
I write this because my mother died from hospital antibiotics.  The hospital protocol killed her.  Due to a weakness, she was taken to the Emergency Room where after a series of useless tests the ER doctor assigned her a room--you guessed it--for more tests.  Once they learned of her full insurance coverage, the hospital protocol is to treat anyone coming in as an ATM from which to perform cash withdrawls.  Once she was hospitalized, the doctors put her on an IV of Zosyn.  It was slow-drip biological trauma, slowly and effectively destroying any of her remaining good bacteria, leaving her system open to stress and weakness.  And true to the intentions of that restorative protocol [burning sarcasm], ten days later she was dead.  The best place for your loved ones to be IS OUT OF THE HOSPITAL.  Don't just sign their life over to aloof and fully-licensed professionals.  Instead, provide your loved ones with the protocol that Bill Sardi offers up above:

Low-fat diets that never satisfy and only induce more food craving instead of a varietal diet rich in prebiotics like mushrooms, pickles, sauerkraut, miso soup, bran, oats, barley that populate our gut with bacteria that produces lean, non-diabetic humans. 

Find ways to deliver these in delicious, life-affirming dishes.