ANTIOXIDANTS

GINSENG 
Which is best: American or Korean Ginseng?
This article makes a convincing case for Red Korean Ginseng.

GLUTATHIONE
Dr. Levy recommends a liposomal encapsulated Glutathione, the most important intracellular antioxidant.  Vitamin C is your most important extracellular antioxidant.  Nice distinction.  



 


MAGNESIUM
A shortage of dietary magnesium has been repeatedly shown to be associated with an increased risk of a sudden-death heart attack. Unequivocally, a shortage of magnesium from the American diet, in particular, the absence or shortage of magnesium in drinking water, is directly related to a sudden-death heart attack. [Epidemiology 10: 31-36, 1999; Heart 82: 455-60, 1999; American JournalEpidemiology 143: 456-62, 1996] Out of 750,000 heart attacks in the USA annually, an estimated 340,000 deaths occur within one hour of a heart attack. [Journal Nutrition Health Aging 5: 173-78, 2001]
This should come as hopeful news.  
One study showed the relative risk of sudden-death heart attack is more than 1.5 times higher among adults who consume on average 105 milligrams of magnesium a day compared to adults who consume 233 milligrams a day. [Magnesium Trace Element Research 9: 143-51, 1990]
That's good, right?  If you consume only 105 mg of magnesium, you're not getting enough to stave off death. Though there are no guarantees, taking adequate amounts of magnesium, meaning 300 milligrams and over, will stave off a sudden-death heart attack.  
Of the minerals removed during water softening, magnesium is the only mineral found to be deficient in the heart muscle of sudden-death heart attack victims. [Science 208: 198-200, 1980] In an animal experiment, no rodents experienced a sudden-death heart attack when magnesium levels were adequate, whereas 4 of 11 rodents with low magnesium levels experienced a sudden lethal heart muscle spasm. [Journal American College Cardiology 27: 1771-76, 1996] 
This chart is absolutely stunning.  What the hell has happened to our food and nutritional supplies?  
Progressive decline of dietary magnesium consumption Years Magnesium intake milligrams per day 
1900-08: 475-500 mgs/day.
1909-13: 415-435 mgs/day.
1925-29: 385-398 mgs/day.
1935-39: 360-375 mgs/day.
1947-49: 358-370 mgs/day.
1957-59: 340-360 mgs/day.
1965-76: 300-340 mgs/day.
1978-85: 225-318 mgs/day.
1990-2002: 175-225 mgs/day.
[Magnesium Trace Elements 10: 162-28, 1997]

On supplementation, do not expect policymakers to insist it get put into foods.  Your food consumption will not provide you with the magnesium you need to stay alive. Sardi explains why.

Only universal magnesium supplementation is likely to make up for such a widespread mineral deficiency. Foods cannot easily be fortified with magnesium because it is a bulky mineral that would alter the consistency and taste of flour and foods. Magnesium cannot be added to tap water because it would erode piping. Either magnesium pills or magnesium added to bottled water would make up for this mineral deficiency. Currently, only 5 major brands of bottled water provide a desirable measure of more than 75 milligrams of magnesium per liter and only one brand has a ratio of magnesium that exceeds that of calcium.

To get magnesium to the brain, Magtein is your best option there.  I've tried a couple of brands.  Here is one.  

Dr. Mildred S. Seelig
VITAMIN B
Here, Dr. Thomas Levy says that having a good vitamin B complex is essential.  Would be nice if these guys would recommend a particular product.  

VITAMIN C: THE GREAT ELECTRON DONATOR
As Dr. Thomas Levy refers to osteoporosis as scurvy of the bones and not a calcium deficiency, I thought I would post this quote on vitamin C as the preferred nutrient over calcium for the bones and, in particular, for diseases of the bones, like osteoporosis.

But the most important vitamin Dr. Levy recommends for bone health was a surprise to me. It’s vitamin C. He calls vitamin C the “foundation and cornerstone of strong bones.” And he says osteoporosis is not a calcium deficiency. Instead, it’s “scurvy of the bones.” 
Here’s what he means: Vitamin C is needed to maintain a health balance of bone-building osteoblasts and bone-destroying osteoclasts. It helps new osteoblasts form to build new bone.  It also impedes the destruction of bone by osteoclasts. When your levels of vitamin C are low, you have trouble building new bone and your bone breakdown speeds up.
60 Reasons for Taking Vitamin C, Bill Sardi.

from Whale.to 
"Dr. Levy shows that many viral diseases such as polio, hepatitis, and encephalitis have been consistently cured by high doses of vitamin C given intravenously.....outlines the evidence that many potent toxins are completely neutralized by prompt and vigorous dosing of vitamin C, even though current medicine offers little or no other effective treatments for them. Dr. Levy cites literature that shows vitamin C can completely reverse and clinically cure advanced poisonings from agents such as tetanus toxin, mushroom toxin, barbiturates, snakebite venom, and heavy metals like lead, to name only a few. Because of this toxin-neutralizing ability, Dr. Levy further notes that the scientific evidence supports vitamin C as being an ideal agent for treating many of the infectious diseases that also produce very potent toxins, such as diphtheria, tetanus, and pertussis (whooping cough)."---Book review 2002 
Here is another. . . 
"Six cases of virus encephalitis were treated and cured with vitamin C injections. Two cases were associated with virus pneumonia; one followed chickenpox, one mumps, one measles and one a combination of measles and mumps. In the case that followed the measles-mumps complex, definite evidence was found to confirm the belief that massive, frequent injections are necessary for treating virus infections with vitamin C............A lad of 12 years had a generalized headache a week after having mumps, this followed by malaise, and in 12 hours a lethargic state and a fever of 105°. Admitted to the hospital, he was given 2000 mg. of vitamin C then, and 1000 mg. every two hours. Following the third injection he. was sitting up in bed, laughing, talking, begging for food and completely without pain........Of mumps, 33 cases were treated with ascorbic acid. When vitamin C was given at the peak of the infection the fever was gone within 24 hours, the pain within 36 hours, the swelling in 48 to 72 hours. Two cases were complicated with orchitis. A young man of 23 years developed bilateral orchitis one Friday morning, by seven o’clock that night he was in severe pain, had a fever of 105° and was nursing testicles the size of tennis balls. Vitamin C was started at this time — 1000 mg. every two hours, intravenously. The pain began to subside following the first injection and ceased in 12 hours. There was no fever after 36 hours. The patient was out of bed feeling his old self after 60 hours...........A second boy, aged 11, was allowed to develop mumps to the point of maximum swelling without any therapy, then given vitamin C, 1000 mg. intramuscularly, every two to four hours. This lad was entirely well in 48 hours."--Dr. Klenner The Treatment of Poliomyelitis and Other Virus Diseases with Vitamin C Fred R. Klenner, M.D. 1949
Here is another. . . 
"The use of vitamin C in measles proved to be a medical curiosity. During an epidemic, vitamin C was used prophylactically and all those who received as much as 1000 mg. every six hours, by vein or muscle, were protected from the virus."----Dr. Klenner The Treatment of Poliomyelitis and Other Virus Diseases with Vitamin C Fred R. Klenner, M.D. 1949
I got a million of them. 
"But the ordinary child who gets measles, even the child with a moderate degree of malnutrition and so forth, if you give intravenous vitamin C supplementary to other forms of treatment, the response very often, not always, is absolutely dramatic If you get them early enough. You must get them early. If you delay, and they have been unconscious let us say for days, or a day or two, you cannot reverse it. The damage is permanent. If you get them early, give them this treatment and there is no problem. And that makes me very, very angry because they talk about "Oh, we must stop these kids getting measles" and so forth. Well, all right, I can fix them if they get measles."---Dr. Kalokerinos (International Vaccine Newsletter June 1995)
And one more.
"The matron was convinced that the diagnosis was meningitis so she prepared a lumbar puncture.  I had, however, seen this problem before.  Lumbar punctures performed by me had been negative and the infants died....the trauma of inserting a needle..might result in a [hemorrhage] that might cause spinal cord paralysis.  So I decided to give an injection of vitamin C.  I probably gave as many as 6 injections, each 100 mg.  After half an hour, Mary was normal.  It was hard to believe, but I had performed a miracle!...I found that any viral infection, including measles and hepatitis, could be dramatically 'cured' by administering Vitamin C intravenously in big doses--provided that treatment was commenced early."---Dr. Kalokerinos MD (Medical Pioneer of the 20th century p175)
I mean at some point all the cries about vitamins not doing any good or high doses being dangerous need to be revisited.  That's a light way of saying, "Hey, don't dismiss the value before you check it out."  Yet pharmaceutical drugs responsible for knocking off hundreds of thousands of Americans each, and we're supposed to think that nutritional compounds are dangerous?

Remember this guy?


To me, it is amazing how the FDA, the AMA, and others have worked to discredit vitamin C or otherwise distort its effectiveness.  I met one gentleman who suffered from Hepatitis B.  He was coughing incessantly with a deep phlegmatic cough.  I felt sorry for him, but, too, I didn't want to be around him once he told me that he had liver disease.  I suggested that he take high doses of vitamin C, say 10 grams for a few days.  He replies to me, "I'll have to check with my doctor."  Here was a guy who has very serious liver disease and is still deferring his health to his doctor, who probably knows nothing about nutrition or vitamin supplementation.

Then I read this morning from Bill Sardi
12. There is a concern that maximal upper limits may not accommodate the nutritional needs of specific organs in the body. Nutritional authorities have given too much attention to achieving minimal and maximal blood levels of nutrients, which may not be an adequate measure of nutrients in specific tissues. For example, it has been stated that the blood circulation becomes saturated with vitamin C at about 240 milligrams. Even when saturation has been achieved in the blood plasma, the provision of 2000 milligrams of vitamin C further increases the levels of vitamin C in the aqueous fluid of the human eye by 35 percent. Higher levels of vitamin C are required in the aqueous fluid of the eye than in the blood circulation because the human eye is transparent and is prone to harm by-products of oxidation (hydrogen peroxide) emanating from exposure to solar ultraviolet radiation. Much higher levels of vitamin C are required to prevent cataracts than to prevent scurvy. The daily amount of vitamin C required to prevent cataracts is in the range of 300-2000 milligrams (the equivalent of 6-30 oranges), which exceeds the best dietary consumption (about 200-250 milligrams from consumption of five servings of fruits and vegetables). The National Academy of Sciences (NAS) now considers 2000 milligrams of vitamin C as "toxic." [See my addendum regarding the issuance of new recommendations for antioxidants by the NAS below.] The human eye has a greater need for vitamin C, lutein, vitamin E, glutathione and vitamin A, than most other tissues in the body. 
In that same article, he adds
Furthermore, Maret Traber Ph.D., a member of the NAS panel, says there is "no evidence that proves antioxidant supplements will help people live better longer." [Whole Foods Magazine, August 2000]  Really? There was a UCLA study, which showed that greater than 300 mg of daily vitamin C increases the male life span by six years, a report that was widely reported in Newsweek and other periodicals. [Epidemiology 3: 194-202, 1992] A recent study confirms that finding. [Epidemiology 11: 440-45, 2000]  
Furthermore, one study shows that about 294 mg of vitamin C significantly decreases the risk of cataracts compared to 77 mg. per day (about the level set by the Academy of Sciences). [Clin Chem 39: 1305, 1993] To get that much vitamin C a person would have to consume 5 oranges per day. Daily consumption of vitamin C supplements for 10 years or more results in a 77-83 percent reduction in the prevalence of cataracts. [Am J Clin Nut 66: 911-16, 1997]  
One of the fallacies of current vitamin C research is the use of blood serum levels as the gold standard for establishing recommended daily consumption levels. A 1991 study, conducted at the USDA Human Nutrition Research Center on Aging at Tufts University found that there were "striking differences" in ocular levels of vitamin C among older adults who consume 148 mg of vitamin C from their daily diet (which is 2.5 times the old 60 mg RDA and 1.6 times the current 90 mg recommendation) compared to adults who took 2000 mg daily from supplements. The level of vitamin C in the focusing lens and aqueous fluid of the eye increased by 22-32 percent with consumption of 2000 mg of daily vitamin C supplementation, which affords protection against cataracts. Thus the idea that vitamin C levels reach a saturation point at about 240 mg in the blood serum, and that additional vitamin C is worthless and only washes out in the urine, is dispelled by this research. [Current Eye Research 8: 751-59, 1991] This is the same level of vitamin C that the National Academy of Sciences now consider "risky." [NAS press release April 10, 2000] 
It's vitamin C for the eyes.  Nutrition and the Eyes, Bill Sardi. 

VITAMIN D
Vitamin D Council.  Overdose with D is possible.  The high-range for healthy people is 10,000IU/day.  Toxicity with vitamin D comes at the 40,000IU per day amount.  In fact, even AT 40,000IU per day, you will not experience toxicity; it's only when you go over that amount for several weeks and months that toxic side effects begin to present themselves, namely hypercalcemia: excess calcium builds up on the blood vessel walls.  Any other toxic side effects?  

Be sure to review these other vitamin D sites:  Jack Kruse
, "Vitamin D Is Underestimated," says John J. Cannell, owner of the site Vitamin D Council.  Find an excellent interview with him here.  Then there is the Vitamin D Society.

VITAMIN E
One can also overdose on Vitamin E.  Interesting.  I'd like to know what an overdose amount is and what the toxic effects of an overdose are.  
ZINC
Even Sardi admits that zinc dosage could be different for people when considering age, condition, or health status.  He writes
The recommended daily allowance for zinc is just 11 milligrams per day for adult males and 8mgs for females, but there is no RDA for seniors who typically have difficulty absorbing zinc (possibly due to prevalent H Pylori infection that shuts off stomach acid secretion). 
So seniors need more; so do vegetarians.  Why?
Vegetarians, individuals with H. Pylori infection (about half of the US population) which shuts off stomach acid secretion, individuals taking zinc-depleting drugs (ACE inhibitors, histamine blockers; diuretics; beta blockers; cortisone; estrogen; steroid anti-inflammatories), alcohol, antibiotics, commonly experience a shortage of zinc. 
What are the food sources of zinc?  Oysters and meat.  Sardi explains that
Health-minded individuals are likely to search for zinc-rich foods, but frankly, aside from oysters (74.0 mg zinc per 3 ounces/serving), foods do not provide much zinc (meats providing the most).
Isn’t zinc a metallic or heavy mineral?  Is that safe? 
Compared to other metallic minerals, zinc is relatively harmless, though it should be balanced with 1 mg of copper for every 10mgs of zinc.  Daily consumption of more than 40mgs of supplemental copper is not advised. 
ZINC DOSAGE: 25-40mg/day
It’s best to take 10-25 mg of supplemental zinc on a daily basis, with food to enhance absorption, if [you are] zinc deficient.  If taking more zinc than this, a copper supplement at 1/10th the dose of zinc should also be consumed.  

From Page 12 of his brochure, Bill Sardi defines the supplemental ranges more specifically, 
For adults, supplemental zinc should stay below 34-40mg/day to avoid side effects and not induce a zinc/copper imbalance.  
ABSORPTION: HOW TO IMPROVE ZINC ABSORPTION?
With zinc absorption being such a problem, possibly co-supplementation with fat-soluble vitamins A & D should be considered given that these two vitamins improve zinc absorption.  Vitamin D is known to improve calcium and magnesium status and recently it has been shown to improve zinc levels.  The use of betaine hydrochloride supplement to provide acid to the digestive tract will improve zinc absorption.
Zinc methionine (Optizinc) is a more bioavailable form of zinc. 
Vitamin B6 appears to be needed for the proper utilization of zinc. 

BENEFITS
Let’s see, zinc has “cured” the common cold may be proven to head off Alzheimer’s disease, eradicates H. Pylori prevents mental problems including dyslexia, is a molecular mimic of insulin, etc.  what more could you ask from a dietary supplement?  Why aren’t we all supplementing our diet with zinc acetate, carnosine, orotate, methionine, the best-absorbed forms of zinc?

A healthy thymus gland produces naive T-cells that form antibodies to fight disease.  


A zinc-deficient thymus gland will create a poor quality pool of naive T-cells which will not fight disease nearly as well.  Message?  Get some zinc, preferably OptiZinc, Zinc Citrate, or Zinc Sulfate.  

COMMON ZINC DEFICIENCY SYMPTOMS
Behavioral or learning problems in growing children such as attention deficits, oppositional behavior, reading problems (dyslexia), delayed speech or even autistic symptoms.  
Skin problems such as warts, moles, Athlete’s foot, impetigo, rough skin and rashes, and skin allergies. 
Slow growth
Poor sense of taste and smell.
Low insulin levels.
Diarrhea.
Loss of appetite.
Nausea.
Irritability
Slow wound healing
Hair loss.

The typical North American male consumes about 13mg of elemental zinc/day of dietary zinc; women consume approximately 9mg of elemental zinc/day.  However, because so little zinc is absorbed (~15-20%) it is possible to experience a shortage.
Zinc is needed for the proper growth and maintenance of the human body.  It is found in several systems and biological reactions, and it is needed for immune function, wound healing, blood clotting, thyroid function, and much more. 


FORM OF ZINC
ELEMENTAL ZINC %
TYPICAL DOSE MGS PROVIDES
Zinc Oxide (insoluble)
This is the most ineffective form.  It only produces a laxative effect.
80%
100mg provides 80mg
Zinc Citrate
34%

Zinc Acetate (lozenges)
30%  
This is an excellent form for any cold.  It's extremely effective.  
Zinc Sulfate
23%
220mg provides 60mg
Zinc Carnosine
22%

Zinc Mono-L-Methionine.  Perhaps the best form branded Opti-Zinc.
21%

Zinc Picolinate
20%

Zinc Gluconate
14%
10mg provides 1.4mg

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