Showing posts with label Melatonin. Show all posts
Showing posts with label Melatonin. Show all posts

Monday, April 8, 2024

😯 When taken in Mega doses, MELATONIN has amazing anti-inflammatory & healing effects. Lowered mortality 93% in Covid. Also lowers death in Pneumonia, Sepsis, & more.

Thursday, March 28, 2024

MELATONIN COMBINED WITH ATP FIGHTS CATARACTS


Friday, October 13, 2023

Melatonin has been shown to treat breast, colon, lung, hepatobiliary, ovarian and prostate cancers - which just happen to also be the same cancers that show up after Pfizer or Moderna COVID-19 mRNA Vaccination

Monday, August 14, 2023

" broccoli seedlings closest to the Wi-Fi router grew away from the router. Plants began to several small plants begin to die and mold developed in those Petri plates"

Check out Abstract #2.  Not only is Melatonin neuroprotective, but so is iodine and so is liquid chlorophyll

ABSTRACT #2 

Both in vitro and in vivo, melatonin was effective to prevent oxidative stress/nitrosative stress-induced mitochondrial dysfunction seen in experimental models of AD, PD and HD. These effects are seen at doses 2-3 orders of magnitude higher than those required to affect sleep and circadian rhythms, both conspicuous targets of melatonin action. Melatonin is selectively taken up by mitochondria, a function not shared by other antioxidants. A limited number of clinical studies indicate that melatonin can improve sleep and circadian rhythm disruption in PD and AD patients. More recently, attention has been focused on the development of potent melatonin analogs with prolonged effects which were employed in clinical trials in sleep-disturbed or depressed patients in doses considerably higher than those employed for melatonin. In view that the relative potencies of the analogs are higher than that of the natural compound, clinical trials employing melatonin in the range of 50-100mg/day are needed to assess its therapeutic validity in neurodegenerative disorders.  https://pubmed.ncbi.nlm.nih.gov/22391273/

Tuesday, February 14, 2023

The pituitary releases hormones throughout the endocrine system to ensure physiological functions in our body; the pineal gland is mostly responsible for producing melatonin.

From PubMed  

ABSTRACT

The present study was carried out to investigate if ethanol alters the aromatization of androgens and concentrations of hepatic estrogen and androgen receptors. Hepatic aromatization of androgen to estrogen was significantly increased by ethanol administration. There was a significant increase in serum estrogen level but a decreased circulating testosterone level in alcohol-fed rats. Furthermore, the concentration of estrogen receptors in liver cytosol was significantly higher in alcohol-fed rats (37 +/- 5.3 fmol/mg protein), as compared to the intact control value (21 +/- 4.8 fmol/mg protein). However, hepatic androgen receptor levels were much lower (4.4 +/- 0.5) in alcohol-fed rats than those (10.2 +/- 1.4 fmol/mg protein) in control animals. Similarly, castration increased hepatic aromatization of androgens and concentrations of serum estrogen and hepatic estrogen receptors, but it decreased the contents of circulating androgen and hepatic androgen receptors. These findings indicate that alcohol administration is considered a chemical form of castration, altering the hepatic steroid metabolism and sex hormone receptor contents and contributing to the pathogenesis of feminization. A combination of alcohol-feeding and castration has no synergistic effect on the hepatic steroid receptors and aromatization, but this combination does have a more profound effect in lowering the concentration of circulating androgen.

Here are some foods that raise, or increase, your androgen receptors.  First, knock off the alcohol except for the occasional celebration of personal milestones.  Don't get me wrong.  I love red wine. Would drink it regularly if didn't have all the nasty side effects on the brain and liver.  Those side effects can make a person irritable and grumpy the next day for which you'll need plenty of coffee the next morning to revive yourself.  But alcohol and coffee both deplete your vitamin B stores.  In fact, these beverages are referred to as B blockers because they block the absorption of vitamin B into your tissues.  Because alcohol does have nasty effects on hormones even tissues, I abstained long ago, decades now.  I was always considered a lightweight when friends, relatives, and acquaintances had no problem putting away excessive amounts.  

Coffee does have benefits but too much can drain the brain of B vitamins and deplete the pituitary gland [A MAJOR PLAYER IN YOUR ENDOCRINE SYSTEM, sometimes called "the master gland"] hormones

Which hormones does the pituitary gland make?
The anterior lobe of your pituitary gland makes and releases the following hormones:
Adrenocorticotropic hormone (ACTH or corticotrophin): ACTH plays a role in how your body responds to stress. It stimulates your adrenal glands to produce cortisol (the “stress hormone”), which has many functions, including regulating metabolism, maintaining blood pressure, regulating blood glucose (blood sugar) levels and reducing inflammation, among others.
Follicle-stimulating hormone (FSH): FSH stimulates sperm production in people assigned male at birth. FSH stimulates the ovaries to produce estrogen and plays a role in egg development in people assigned female at birth. This is known as a gonadotrophic hormone.
Growth hormone (GH): In children, growth hormone stimulates growth. In other words, it helps children grow taller. In adults, growth hormone helps maintain healthy muscles and bones and impacts fat distribution. GH also impacts your metabolism (how your body turns the food you eat into energy).
Look at how these idiots describe biological functions.  Science is corrupted.  F**k these compliant bureaucrats.  "assigned"?  
Luteinizing hormone (LH): LH stimulates ovulation in people assigned female at birth and testosterone production in people assigned male at birth. LH is also known as a gonadotrophic hormone because of the role it plays in controlling the function of the ovaries and testes, known as the gonads.
Prolactin: Prolactin stimulates breast milk production (lactation) after giving birth. It can affect fertility and sexual functions in adults.
Thyroid-stimulating hormone (TSH): TSH stimulates your thyroid to produce thyroid hormones that manage your metabolism, energy levels, and your nervous system.
And a few more

But we all want a simplified life. In that case, ignore everything I've said or printed here, and go on about your business.  But if you want to maintain a high level of productivity long into your years, then be vigilant on bodily processes that deliver on productivity.   To keep your pituitary gland functioning at peak levels as you continue drinking coffee, then it would help, help a lot, to be consuming boron.  

The difference between the Pituitary Gland and the Pineal Gland is that the pituitary releases hormones throughout the endocrine system to ensure physiological functions in our body, whereas the pineal gland is mostly responsible for producing melatonin.  People take melatonin supplements to keep the pineal gland producing melatonin.  Boron helps to keep that organ regulated.  Pineal gland is not just for melatonin.  It's also responsible for critical thinking.  For the Pituitary gland, eat red meat, get sunlight at peak hours, 11-2, get Omega-3s through fish oil, and supplement with vitamin D. 

Monday, December 12, 2022

MELATONIN, THE ANTI-CANCER NUTRIENT

The presentation was given by Dr. Frank Shallenberger.  

PureBulk is the site for buying in bulk.  BTW, if you need to phone PureBulk just know that their hours are 7am to 3pm, PST.  They close early.  
 
He explains that people don't die from cancer; they die when the cancer metastasizes.  

He says that with prostate cancer melatonin is a slam dunk. Now he uses additional compounds but melatonin is the main one and he gives it in massive amounts. I just didn't hear a dose amount.  He does say that Professor Russel Reiter in studying mice, gave mice, WHO WERE BRED TO GET BREAST CANCER, large amounts of melatonin and they DID NOT GET BREAST CANCER.  So there's that.  But how much, how much?  Reiter has said previously that he takes upwards of 140mgs of Melatonin/day.  I'd say that if someone has cancer that you'd want to go a little higher.

7 anti-cancer mechanisms of melatonin:
1.  Direct Anti-neoplastic effect.
2.  Decreases cell proliferation at low doses.
3.  Direct cytotoxic effect occurs with higher doses.
4.  Stimulation of cell differentiation.
5.  Induction of apoptosis.
6. Anti-angiogenic.  
7.  A synergistic effect has been found in several types of cancer when it is administered in combination with chemotherapy.  Shocked that he would use chemotherapy.  

Thursday, November 10, 2022

SARS-CoV-2 can upregulate NLRP3 inflammasomes in the brain to induce neurodegenerative disorders, including Parkinson's disease. Melatonin targets NLRP3 inflammasomes. Now you know why MEL is effective against brain fog and memory loss after C-19 infections

High dose melatonin is best for anti-oxidant powers and less for sleep inducement.  But if you're interested, you should read everything about amazing melatonin by Doris Loh.   

Monday, October 31, 2022

"Ultraviolet C Band of light had germicidal properties due to it’s ability to break apart the DNA of organic matter"

UVC is a particular wavelength of light.  

All three bands have germicidal properties that make them beneficial for multiple applications in facility management, including:

Coil Irradiation in HVAC systems to boost energy efficiency and reduce maintenance.

Air Disinfection through the use of Upper Air Germicidal Irradiation units, which is very effective at controlling the spread of influenza virus, the common cold, and most every other airborne pathogen.

Surface Sterilization is a newer application and there are a variety of devices sold that claim to do this.  Although the technology is sound the efficacy of how the different systems deliver the UV-C light to the surfaces to be sterilized/decontaminated is questionable.

    It was discovered way back in the 1890’s that the Ultraviolet C Band of light had germicidal properties due to it’s ability to break apart the DNA of organic matter.

Thursday, October 27, 2022

You're no yellow-bellied rat . . . but as a precaution, take Melatonin . . .

Hypoperfusion is a term that describes "a reduced amount of blood flow". When ischemia develops due to low blood flow, we may describe this as "hypoperfusion". Causes for hypoperfusion include low blood pressure, heart failure or loss of blood volume.

Tuesday, October 4, 2022

Melatonin has shown significant benefits in reducing cardiac pathology, and preventing the death of cardiac muscle in response to ischemia-reperfusion . . .

Melatonin has shown significant benefits in reducing cardiac pathology, and preventing the death of cardiac muscle in response to ischemia-reperfusion in rodent species.  Moreover, melatonin may also prevent the hypertrophy of the heart muscle  under some circumstances, which in turn would lessen the development of heart failure.

MELATONIN: For neuro-protection, not just sleep inducement, a lot melatonin is required: 50-100mg.

Below are the sections of each abstract that I thought were interesting and helpful. 

ABSTRACT #1

Melatonin is selectively taken up by mitochondrial membranes, a function not shared by other anti-oxidants, and thus has emerged as a major potential therapeutic tool for treating neurodegenerative disorders. Multiple in vitro and in vivo experiments have shown the protective role of melatonin for preventing oxidative stress-induced mitochondrial dysfunction seen in experimental models of PD, AD, and HD.  https://pubmed.ncbi.nlm.nih.gov/26087000/

For neuro-protection, not just sleep inducement, a lot melatonin is required: 50-100mg.    

ABSTRACT #2

Both in vitro and in vivo, melatonin was effective to prevent oxidative stress/nitrosative stress-induced mitochondrial dysfunction seen in experimental models of AD, PD and HD. These effects are seen at doses 2-3 orders of magnitude higher than those required to affect sleep and circadian rhythms, both conspicuous targets of melatonin action. Melatonin is selectively taken up by mitochondria, a function not shared by other antioxidants. A limited number of clinical studies indicate that melatonin can improve sleep and circadian rhythm disruption in PD and AD patients. More recently, attention has been focused on the development of potent melatonin analogs with prolonged effects which were employed in clinical trials in sleep-disturbed or depressed patients in doses considerably higher than those employed for melatonin. In view that the relative potencies of the analogs are higher than that of the natural compound, clinical trials employing melatonin in the range of 50-100mg/day are needed to assess its therapeutic validity in neurodegenerative disorders.  https://pubmed.ncbi.nlm.nih.gov/22391273/

ABSTRACT #3

Melatonin is a tryptophan-derived ancestral molecule evolved in bacteria.

Throughout the aging process melatonin levels tend to reduce and as a manifestation of this, many symptoms in organisms' homeostasis, such as deterioration in adjustment of cellular clocks, are commonly seen. In addition, due to deterioration in mitochondrial integrity and functions, immunity decreases, and lower levels of melatonin renders older individuals to be more susceptible to impaired redox modulation and age-related diseases.  https://pubmed.ncbi.nlm.nih.gov/35895186/

Thursday, September 29, 2022

Well, well, well . . . . Nattokinase degrades the spike protein floating in the blood and attached to the cell

You don't get any closer to a cure for COVID or for the toxic spike protein than Nattokinase.  And I was recommending this to everyone by June 2021.  Few listened, so I shipped a couple of small bottles via Amazon anyway.  Never heard back, whether they liked it or not.  So that was a sunk cost; at least now they know about it.  So as you take Nattokinase to degrade and neutralize the spike protein, be sure to take lots of melatonin to reverse some of the aging effects of the vaccine.

Anti-Aging Melatonin to the Rescue

Be sure to get a second opinion on the anti-aging benefits of melatonin.  Dr. Russel Reiter says

I have a supply of melatonin with me at all times.  If I have a stroke or heart attack, I'll immediately load up on melatonin.  Based on what I know, I will take all the melatonin I can, as fast as I can.

Friday, August 26, 2022

MELATONIN: anti-Covid, anti-inflammatory, radioprotective, anti-cancer, safe supplement when taken at high doses (100-2000mg).

Melatonin significantly decreased the virus levels in blood and brain . . . 

Friday, August 12, 2022

Dr. Russell Reiter on Melatonin

  
Thanks to Chris @ Chris Beat Cancer.  

Show Notes
*  How Dr. Reiter got into melatonin research [1:23]
*  What melatonin does in the body [3:28]
*  How blue light inhibits melatonin production [7:05]
*  How melatonin is passed to the fetus and newborn [12:00]
*  The anticancer benefits of melatonin [15:25]
*  How pharmaceutical drugs suppress melatonin production [18:40]
*  When should melatonin be taken during the day? [22:47]
*  Does taking melatonin affect natural production? [24:36]
Blind people have lower rates of cancer due to the higher circulating melatonin in their blood.  [27:22]
*  Older people need more melatonin [29:20]
*  How melatonin can reduce the impact of Covid-19 [31:15]
*  The impact of alcohol and caffeine on melatonin production [34:45]
*  Melatonin acts as an antiviral [37:24]
*  How sunlight helps with the production of melatonin [44:35]
*  Melatonin can reduce the likelihood of metastasis [50:45]

Thursday, June 9, 2022

MELATONIN'S UNEXPECTED BENEFITS: slows aging, Prevents . . . Parkinson's and Alzheimer's, protects against ionizing radiation, macular degeneration, treats cancer . . .

This was interesting.  

It's a review by Dr. Gary Gonzalez of Dr. Russel [one L] Breiter's book on melatonin.  Most of us, including myself, think of melatonin as a sleep aid or more recently as a valuable antioxidant.  Reiter explains just how valuable it is for longevity and radical health.  

The first longevity product that I'd ever heard or read about was Resveratrol and IP6.  IP6 was a longevity compound because it managed the EXCESS iron floating around in our blood, out of the tissue, as what is called "Unbound iron."  The excess iron produces an inflammatory protein that, if left untreated, leads to chronic diseases like arthritis, 

FEMALE LONGEVITY

The end result is even more compelling. For example, Reiter explains that five separate studies have shown that older women produce more melatonin than older men-suggesting a possible explanation for the long-observed female longevity factor." He details findings showing a marked correlation between brain functioning in older age and melatonin levels.

Shielding DNA From Free Radicals

Reiter explains melatonin's effects on the immune system of aging animals and determines whether or not these actions also apply to humans. Most importantly, he shows how melatonin fits in with the free radical theory of aging.

He explains that melatonin is found in the greatest abundance in the nucleus of the cell, where it shields the DNA molecule itself from free radical damage better than any other known substance. Reiter describes his own studies in which melatonin has protected DNA from free radicals generated by radiation, carcinogens, bacterial toxins, and most important the process of using oxygen for fuel.

UNEXPECTED BENEFITS

Even if you have no sleeping issues, anyone over 40 should be taking melatonin.  19 Research papers reveal that melatonin promotes all of these unexpected effects [in no particular order, though numbered:

1.  Protects against viral and bacterial infections.

2.  Prevents cardiovascular disease and high blood pressure. 

3.  Reduces oxidant stress and inflammation and slows aging. 

4.  Prevents neurodegenerative diseases such as Parkinson’s and Alzheimer’s. 

5.  Improves menopause therapy. 

6.  Protects against ionizing radiation. 

7.  Prevents macular degeneration. 

8.  Prevents and treats cancer.

Okay, so with all of these benefits, the only thing to consider is how much does, or should, one take?  First, I would say do a trial run.  By that I mean start with smaller amounts, say, 3mgs, and see how you feel upon waking, whether or not you can tolerate melatonin to begin with, or tolerate that amount.  When I first tried melatonin, I woke up and could barely raise my arms, and my legs felt like bricks.  But when I was working a physically demanding job for a few years, I noticed that the only way to turn the pain off was excess melatonin, and excess was 5 to 10mgs back in 2018.  Since then, I've been taking upwards of 12 to 20mgs, but not every night.  For, at least in my case, melatonin doesn't deliver a deep sleep for me.  But I still take it for the other unexpected benefits listed above.  

So how much should you take?  The answer is contingent on several factors.  One, if you've got a serious disease, like cancer, then you want to take more.  Bill Sardi recommends 15-30mgs nightly for cancer treatment in conjunction with several other compounds.  

Saturday, May 21, 2022

MELATONIN: NOT JUST A SLEEP AID BUT ". . . THE MOST POWERFUL ANTIOXIDANT TOOL IN THE WORLD"?

I love her claim that melatonin is a more powerful antioxidant than glutathione, which is considered the master antioxidant.  Imagine the healing that could take place if you took both glutathione AND melatonin.  Be sure to open up that thread by clicking on Natural Immunity's Twitter link.  Melatonin benefits go beyond anticancer.  It keeps our skin healthy and youthful [through] two major mechanisms. It has antioxidant effects that neutralize oxidative damage from the sun, and by stimulating growth receptors in the skin.  NaturalImmunity goes on to say that 

Melatonin may have a profound effect on stroke & heart attack! 🙌 Take w/in 1st 2 hrs. Based on studies, if were me, I'd take ~2000mg, since oral bioavail is low (& that amt has been shown 2b safe). Then 100mg+ every hour or so for 24/48 hrs. (Not medical advice)!

Christopher Wark of Chris Beat Cancer interviews Dr. Russell J. Reiter.  A powerful interview here on how necessary darkness is for our circadian rhythms and our health.  Modern life with night lighting is fairly new in our evolution, disruptive of natural processes, and disease generating.  So embrace the darkness.  Be sure to check out the show notes in the link, "Chris Beats Cancer" above.  Here is a sampling from those notes:

Melatonin acts as an antiviral [37:24]
-How sunlight helps with the production of melatonin [44:35]
-Melatonin can reduce the likelihood of metastasis [50:45]

Clearly, the antioxidant action of melatonin is quite powerful as an anti-cancer compound. Bill Sardi included it in his nutritional compound regimen for cancer, in fact, 15-30mg of melatonin per night.  So there is credible consensus on the anti-cancer benefits of melatonin.


I have to say that any time I hear or read about the anti-aging benefits of melatonin, or any product, my ears perk up.  Antiaging means that you only slow down the aging process.  In some cases, it may be possible to reverse aging processes, like alopecia, or hair loss, this can be reversed with Rutin, Pumpkin Seed Oils, and B5.  This video, which I didn't have the time to watch all the way through, highlights that 1) Melatonin is an ancient molecule.  That's interesting, but what is the relevance of that?  What benefits are derived from its ancient characteristics?  2) It's found in bacteria and every organism between bacteria and mammalians.  Its structure has never changed throughout its evolution, what that means is that the structure of melatonin in bacteria is identical to the structure of melatonin in humans.  Whoa.  Now that is something, but what does that tell us?  That melatonin means life itself?  3) it is not toxic at any dose. 4) it exists in every species that is currently living or that has ever existed.  I mean what is not to like?  For optimal cellular physiology.  Melatonin exhibits in the blood circadian rhythm.  [7:38] "Melatonin is a very strong anti-cancer agent."  It influences the immune system, metabolism, gastro-intestinal function.   


Show Notes from Chris Beat Cancer

-How Dr. Reiter got into melatonin research [1:23]
-What melatonin does in the body [3:28]
-How blue light inhibits melatonin production [7:05]
-How melatonin is passed to the fetus and newborn [12:00]
-The anticancer benefits of melatonin [15:25]
-How pharmaceutical drugs suppress melatonin production [18:40]
-When should melatonin be taken during the day? [22:47]
-Does taking melatonin affect natural production? [24:36]
-Older people need more melatonin [29:20]
-How melatonin can reduce the impact of Covid-19 [31:15]
-The impact of alcohol and caffeine on melatonin production [34:45]
-Melatonin acts as an antiviral [37:24]
-How sunlight helps with the production of melatonin [44:35]
-Melatonin can reduce the likelihood of metastasis [50:45]

Tuesday, January 25, 2022

MELATONIN CAN RE-SENSITIZE CANCER CELLS TO THERAPY

Sunday, January 23, 2022

MELATONIN: EXCELLENT FOR CARDIOVASCULAR DISEASE