SAMA HOOLE: "We're running a population-wide starvation experiment and calling it health advice," thanks to the founder of the Mediterranean Diet.

1944: Ancel Keys runs Minnesota Starvation Experiment.

He puts 36 men on semi-starvation diet for 6 months: 1,570 calories. High-carb, low-fat, low-protein.

Results within weeks:
- Food obsession
- Depression
- Irritability
- Loss of libido
- Social withdrawal
- One subject… pic.twitter.com/0uENPYLYth

— Sama Hoole (@SamaHoole) November 29, 2025

1944: Ancel Keys runs Minnesota Starvation Experiment. He puts 36 men on semi-starvation diet for 6 months: 1,570 calories. High-carb, low-fat, low-protein. Results within weeks: - Food obsession - Depression - Irritability - Loss of libido - Social withdrawal - One subject cuts off three fingers in frustration Keys documents this meticulously. Publishes 1,400-page book: "The Biology of Human Starvation." His conclusion: Semi-starvation causes severe physical and psychological damage. Now here's the interesting part: Keys' starvation diet: 1,570 calories. High-carb. Low-fat. Modern "healthy weight loss diet": 1,500-1,800 calories. High-carb. Low-fat. They're nearly identical. Keys documented this causes food obsession, depression, metabolic adaptation, intense hunger, psychological distress. Then spent the rest of his career promoting low-fat diets. 1960s-present: Dietary guidelines recommend calorie restriction, low-fat, high-carb. This is Keys' starvation diet. Rebranded as "healthy eating." Results, 1960-2025: - Obesity up 300% - Depression epidemic - Food obsession normalised - Eating disorders skyrocketing These are the exact symptoms Keys documented in his starvation experiment. We're running a population-wide starvation experiment and calling it health advice.