Dysfunction in regulation of condensates drive neurodegeneration, cancer, and viral infection. Melatonin is a regulator of biomolecular condensates,

Biomolecular condensates are the holy grail in drug discovery because they allow access to undruggable pathways and targets. Dysfunction in regulation of condensates drive neurodegeneration, cancer, and viral infection. Melatonin is a regulator of biomolecular condensates, 1/2 pic.twitter.com/u05RjNvDAO

— Doris Loh (@DorissLoh) August 18, 2022

The journal Nature explains,

Biomolecular condensates are micron-scale compartments in eukaryotic cells that lack surrounding membranes (they're self-forming) to concentrate proteins and nucleic acids. These condensates are involved in diverse processes, including RNA metabolism, ribosome biogenesis, the DNA damage response and signal transduction. 

Melatonin is a powerhouse compound.  Amazing. 

 

And this the creator made the organizing concept of these organelles pretty clear and fun.