Showing posts with label Vitamin D3. Show all posts
Showing posts with label Vitamin D3. Show all posts

Thursday, December 14, 2023

CHEMOTHERAPY CAN'T HOLD A CANDLE TO VITAMIN D3

from Chris Beat Cancer.

BIG TAKEAWAYS

Sunshine is the best source of vitamin D, but most people don’t get enough sun, especially in the winter. That’s where supplementation comes in.

The ideal vitamin D blood level for viral infection prevention is above 50 ng/ml.

The target vitamin D blood level for cancer prevention and healing is over 40 ng/ml, but higher, between 60-100 ng/ml might be better.

Magnesium, K2, exercise, zinc, resveratrol, curcumin and omega-3’s all help vitamin D3 work better.

I take 5,000 to 10,000 IU of D3 per day depending on the season.

Children can safely take 1,000 IU of D3 per 25lbs of body weight per day.

Vitamin D3 is healthy for humans and rats at appropriate doses.

AN OPTIMAL BLOOD LEVEL OF VITAMIN D IS ESSENTIAL FOR A STRONG IMMUNE SYSTEM 

We have an epidemic of vitamin D deficiency. It’s estimated that nearly half of Americans have “insufficient” vitamin D levels (under 29 ng/ml) and 14 percent are deficient (under 19.6 ng/ml).

Vitamin D blood levels of 50 ng/ml or higher have been found to protect against respiratory infections like influenza or corona-type viruses. D3

Vitamin D increases the production of cathelicidins, anti-microbial peptides that destroy viruses, bacteria, parasites, and pathogens.

Adequate sunshine and/or supplementing with Vitamin D3 appears to be one of the cheapest and best ways to support your innate immune system against flu and corona-type viruses.

A review of 25 trials published in the British Medical Journal in 2017 concluded that vitamin D supplementation clearly protects against acute respiratory tract infections, especially for those deficient in D3.

Researchers found that daily or weekly dosing was more effective than a large one-time dose.

The review indicated that for every four people given vitamin D one case of respiratory infection was prevented. Vaccination typically must be given to 44 people to prevent one case of respiratory infection. Based on this, it appears that Vitamin D supplementation might be 10 times more effective at preventing the flu than a flu shot.

A randomized trial that gave vitamin D3 to Japanese schoolchildren found that those who were given 1200 IU of vitamin D per day from December through March had nearly half as many cases (10% vs 18%) of influenza A than those in the placebo group. The children taking D3 also had fewer asthma attacks (2 vs 12).

Supplementing with 5,000–10,000 IU per day of D3 may be necessary to reach protective blood levels, depending on multiple factors, which I discuss below.

VITAMIN D for CANCER PREVENTION AND HEALING 

In 2016, a landmark study published in PLOS ONE found that women over 55 with blood concentrations of vitamin D higher than 40ng/ml, had a 67% lower risk of cancer compared to women with levels lower than 20ng/ml.

“We have quantitated the ability of adequate amounts of vitamin D to prevent all types of invasive cancer combined, which had been terra incognita until the publication of this paper,” said Cedric Garland, researcher, and adjunct professor at the UC San Diego School of Medicine Department of Family Medicine and Public Health. (Note: they excluded skin cancer)

The RESEARCHERS THAT OPTIMAL LEVELS FOR CANCER PREVENTION ARE BETWEEN 40 and 60ng/ml, (100-150 nmol/L) AND THAT MOST CANCERS OCCUR IN PEOPLE WITH VITAMIN D BLOOD LEVELS BETWEEN 10 and 40ng/ml.

The study did not reveal whether supplementation or sun exposure was the best way to obtain vitamin D. However, the researchers concluded that vitamin D only starts protecting against cancer once you get your blood level up to 40 ng/ml. They noted that more health benefits were observed at even higher levels.

Another study from 2015 showed a 55% lower risk of colorectal cancer in women with vitamin D concentrations of 30ng/ml or higher compared to those lower than 18ng/ml.

A 2018 pooled analysis of 17 studies found that D levels between 40-50 ng/ml (75-100 nmol/L) are related to a statistically significant, substantially lower colorectal cancer risk in women.

HIGHER THAN 60ng/ml COULD BE EVEN BETTER . . .  2005 study found that women with blood concentrations of vitamin D higher than 60ng/ml had an 83% reduction in breast cancer compared with those lower than 20ng/ml.
I’ve observed many doctors and experts recommend that cancer patients shoot for the 60-80 ng/ml range. And even though most of these studies involved women, I think we can safely assume that men will also drive the same anti-cancer benefits from vitamin D.

D3 SUPPLEMENTATION INCREASES SURVIVAL IN P53-POSITIVE DIGESTIVE CANCERS 
A 2023 study of 2000 IU D3 supplementation per day for patients with digestive tract cancers (esophageal, gastric, small bowel, and colorectal), found that 5-year relapse-free survival was almost three times higher in the vitamin D group (80.9%) than the placebo group (30.6%) specifically for patients that were “p53-immunoreactive,” which means they had anti-p53 antibodies in serum and p53 protein in more than 99% of cancer cells tested.

THE SUNSHINE VITAMIN (If you can get it)
The best source of vitamin D is sunshine, and sunshine produces a cascade of health benefits beyond vitamin D production. For this reason, aim for 10-20 minutes of sunshine per day on as much of your body as possible.
But unfortunately, it’s not that simple, the amount of D3 you can get from the sun is determined by multiple factors: your age, your BMI, your skin tone, your distance from the equator, the season of the year, and the weather.

If you live above 37 degrees north of the equator – in the U.S., that’s north of Washington, D.C., and north of the Utah/Arizona border – you probably aren’t getting enough UVB exposure to naturally produce adequate amounts of vitamin D year-round.

For example, a fair-skinned person living in New York gets about 1,000 IU of D3 in about 4 minutes on a sunny day in July. That’s really good! But in January however, it would take them ten times longer, about 40 minutes of sunshine. If it’s cloudy or smoggy, that can block as much as 60% of D3-producing UV rays from the sun.
A person with dark skin needs about four times more sunshine to produce the same amount of D3 as a fair-skinned person. Obese people have been found to have 50% less D3 in their blood than non-obese people. And a 70-year-old makes about 75% less D3 than a 20-year-old.

Basically, you need an advanced degree in calculus to figure out how much vitamin D3 you can actually get from sunshine. I try to get a few minutes of sunshine every day, and I take a D3 supplement year-round.

DOES SUNSCREEN BLOCK D3 PRODUCTION?
Some sources claim that sunscreen with SPF 8 blocks vitamin D3 production by 95% and that SPF 15 or more blocks vitamin D3 by 99%. There is debate about this. I suggest, if you’re going to be in the sun all day, like at the beach, give your skin a few minutes of sunshine before applying sunblock. This is what I do.

Pro Tip: There is a smartphone app called D Minder Pro, which tells you how much vitamin D you will absorb on any given day based on your time in the sun, your location, the weather, your age, skin type, etc.

SOME PEOPLE CAN'T GET D FROM SUNSHINE 
Intracellular bacteria can block Vitamin D Receptors preventing absorption of vitamin D. Inflammatory and autoimmune diseases accompanied by low 25 (OH)D and high 1,25 (OH)2D is indicative of this phenomenon. EBV, HIV, TB, aspergillus fumigatus, and Mycobacterium leprae are known to lower or block Vitamin D Receptor activity. Vitamin D possesses antimicrobial properties against both Gram-positive and Gram-negative bacterial species and was even used to treat tuberculosis before antibiotics came along. Vitamin D supplementation could help increase the activity of Vitamin D Receptors by killing intracellular bacteria.

ACTION STEPS
Check your vitamin D3 level. You can order a test kit from home at Grassroots Health

Your doctor can also order a vitamin D panel with your next set of blood work, or you can get it done at a walk-in testing clinic in your area. Order through www.yourlabwork.com

Depending on your current D3 level and your target level, you could take 1,000-10,000 IU per day, then retest in 30-90 days and adjust accordingly. It may take a few months to get your blood levels up.

VITAMIN D CO-FACTORS 
You need magnesium to absorb vitamin D. Magnesium deficiency shuts down the vitamin D synthesis and metabolism pathway. Plant foods with high levels of magnesium are dark leafy greens, beans, nuts, avocados, and whole grains. Megafood also makes a great whole-food magnesium supplement.

Exercise, resveratrol, zinc, omega-3s, quercetin, and curcumin also help increase vitamin D absorption.

WHAT ABOUT K2?
K2 is not necessary for D3 absorption, but vitamin D increases calcium absorption and K2 helps your body incorporate calcium into your teeth and bones and prevents it from building up in the wrong places, like your arteries.

K2 is present in animal foods and fermented plant foods like natto and sauerkraut. Vegetables are rich in K1 which is converted to K2 by bacteria in your gut. If you are taking high doses of D3 you may need to supplement with K2.

Generally speaking, it is recommended that for every 5,000-10,000 IU of D3 you take, also take 100 mcg of K2 mk7. Some research indicates that it may be better to take D3 and K2 separately instead of together. The jury is still out on that…

WHAT FORM TO TAKE?
I recommend vitamin D3 as cholecalciferol. That is the form that has been widely tested on humans for decades. One brand I don’t recommend is Garden of Life Vitamin Code Raw D3, which does not contain cholecalciferol. I took that supplement for over a year and it did not raise my D3 levels.

I take vitamin D3 5000 IU gelcaps from Better Way Health.  I like their products, and as an affiliate partner, I negotiated a discount for my readers. You can use the coupon code “chris” to get 10% off your order. If you sign up for auto-ship, you’ll save another 15%, for a total of 25% off your order every month. I also take their Curcumin Extra Strength (C3 Complex with Bioperine) for its anti-cancer and anti-inflammatory benefits and their Beta Glucans for additional immune support.

There are several other brands of D3 I like in my Amazon store (www.chrisbeatcancer.com/amazon) like Pure Therapro Vegan 3 and Thorne liquid D3 with K2. Liquid D3 drops are easier to give to kids.

D3 MEGADOSING STRATEGY 
If your D3 level is in the danger zone (under 19.6 ng/ml) and you want to get it up quickly, you may benefit from megadosing with 50,000-100,000 IU per day for 7 days then continuing with 50,000 IU once per week or 5,000-10,000 IU per day. Biotech Pharmacal D-50 is a 50,000 IU D3 capsule designed for megadosing and/or once-per-week supplementation.

IS D3 RAT POISON?
Yes, cholecalciferol is used as rat poison. But don’t panic. As you know, with all things, the dose determines the poison. For example, drinking three gallons of water in an hour is likely to kill you. The D3 dose given to poison rats is the equivalent of over 4 million IU for a human. That would be like taking 2000 capsules of 2000 IU D3. The reason D3 is used to kill rats is because, unlike many other poisonous compounds, it’s essentially tasteless. It can be mixed into rat bait and they will actually eat it. But guess what happens when rats are given appropriate doses of D3 for their body weight.  Their health improves! Like increases in bone mass and strength, improved insulin resistance, and even preventing fatty liver and high blood pressure caused by eating a Western diet.

Sources
NIH
Science Daily
Eureka Alert
New Hope
Riordan Clinic
How Stuff Works

Friday, April 14, 2023

VITAMIN D3: zero mortality at approximately 50 ng/mL

Highlights from Walter's article:

a) As is well known, the Spike Protein uses ACE2 (among many other) receptors to attach to cells and cause infection. This interacti on with ACE2 causes downregulation of the expression of ACE2. ACE2 cleaves Angiotensin II inactivating its deleterious effects when its levels are too high. Vitamin D stimulates ACE2 expression, thereby enabling the cleaving of Angiotensin II.

b) zero mortality at approximately 50 ng/mL D3.

c) the INTERNAL cell ability of Vitamin D protects DNA and activates tumor-suppressing genes and simultaneously inhibits oncogenes (cancer-inducing genes).  

d) Vitamin D3 activates tumor suppressor gene

Wednesday, March 15, 2023

"exposure to prescribed vitamin D supplements was associated with 40% lower incidence of dementia during a ten-year period."

Saturday, November 9, 2019

Vitamin D deficiency linked to muscle weakness in older adults



This interview of Dr. Robyn Balden, a vitamin D expert, was excellent.  She talks about the role that vitamin D plays on the brain, on overall health, on immunity, aging, and other situations.  She also discusses what the limits of vitamin D are, how much people should be taking when they first start, and other scenarios.  It's not that long.  Give it a listen.  I call it a must-listen because she covers points I hadn't heard of before in a very short time.  Saving me time.  I like that.  


Saturday, January 13, 2018

ESTROGEN REPLACEMENT, NOT CALCIUM SUPPLEMENTS, DESCREASES OSTEOPOROSIS BONE FRACTURES BY 25% to 50%.

Metal to bone, even in dentistry or especially in dentistry, can be horrific.  So why not take care now to stem the tide on that prospect?  Fewer and fewer things are inevitable in this world thanks to science.  It is true that a hip replacement can save a life.  And can keep people productive and active.  I don't really know.  I know only one person who has had a hip replacement.  Check out Stephen Tower's experience with his hip replacement done in 2006.
When Stephen Tower’s right hip gave out in 2006, he asked his surgeon to implant an artificial one — specifically, a metal-on-metal hip called the ASR XL, made by Johnson &Johnson. He knew what he was talking about: As an orthopedic surgeon, Dr. Tower specializes in complex hip replacements. But what he knew wasn’t enough to protect him from a defect in the device.Five years after his surgery, and in excruciating pain, Dr. Tower underwent more surgery, this time to have the device replaced.
When the surgeon sliced into his hip, what he saw looked like a crankcase full of dirty oil. Tissue surrounding the hip was black. Cobalt leaking from the ASR hip had caused a condition called metallosis, destroying not only local muscle, tendons and ligaments, but harming Dr. Tower’s heart and brain as well. 
That can't be good.  So to avoid this problem down the line, be sure to keep your bones strong.  But with what?  Calcium?  Hardly, particularly for post-menopausal women.  This fact made me blink
Strangely, modern medicine acts as if it is baffled and dumbfounded when it is commonly reported that arteries calcify at a rate that correlates with loss of calcium from bone. This is called the "calcification paradox." There is no paradox, except in the minds of ill-informed physicians.
Wow.  As our limbs grow thinner and we lose bone, the calcium does not exit the body; it only transfers to our arteries, hardening them.  Ouch.  But there is an antidote for this: vitamin D3.

From that same Bill Sardi article, he writes
Estrogen sends a signal for calcium to be held in bones. Without that signal, calcium slowly exits bone and is deposited in arteries. The risk for heart disease rises by 360% with the onset of menopause. Calcium released from bone is deposited in arteries, which causes loss of elasticity, inability to control blood pressure, and eventual blood clots or calcium plaque that can block a coronary artery that feeds the heart oxygen. This arterial blockage is called a heart attack.
The point is that post-menopausal women do not want to be supplementing with calcium.  Instead, supplement with estrogen. 
Calcium supplementation in menopause is futile. Studies do show calcium supplementation helps to slow down the loss of calcium from bone, but there is no gain in bone density. On a net sum basis, calcium is still being lost from bone.
Why don't women simply replace estrogen? 
The answer to the above question is that women have literally been frightened away from estrogen replacement without adequate scientific evidence. This is despite the fact that estrogen replacement decreases the incidence of osteoporotic bone fractures by 25% to 50%.  Instead, doctors now prescribe alternate medications to inhibit bone loss (Fosamax, Boniva, Actonel) which produce abhorrent side effects such as esophageal erosion, stomach irritation and even jaw-bone damage.
Hormone replacement therapy reduces bone turnover, increases bone mineral density (BMD), and decreases vertebral fracture rates by approximately 40%, even in women over 70 years of age.
It will come as a surprise to learn that abandonment of hormone replacement therapy in 2002 was a false alarm. Investigators were recently surprised by the "enormous discrepancy they found between the belief that hormones are dangerous and the lack of supporting data."

Sunday, September 10, 2017

"deficiency of vitamin D results in poor muscular tone which may predict the need for C-Section"

It is hard to deny any longer the remarkable protective benefits of Vitamin D3.  There is even a website dedicated to its information and application, called the VitaminDCouncil.  The very first remedy that I'd heard improved by Vitamin D3 was the seasonal affective light disorder or SAD for short.  Always with the acronyms.  The prescription for this condition ranges between 1,000 to 4,000 IUs.  I don't know what is enough, but I do know that taking a lot more during the day is more beneficial.  Now you don't take 10,000 IUs all at once.  But taking 3,000 to 5,000 IUs three times a day will put your skin, your bones, and your brain in excellent condition.  
Why do we take vitamins to begin with?  To improve conditions without using pharmaceutical drugs, right; that, and to see if supplements can help us circumvent surgery.  Bill Sardi has an 2010 article on just this topic, "How to Avoid Ten Common Surgical Procedures With Dietary Supplements."  In this article he explains the cause why some women require a C-Section and why their 
On C-Sections, he writes
Of great interest is a recent report showing a deficiency of vitamin D results in poor muscular tone which may predict the need for C-Section.  Women with low Vitamin D levels were nearly three-times more likely toundergo C-Sections.  Vitamin D supplementation is suggested throughout pregnancy.  The 400-IU recommendation is insufficient to raise blood levels.  Daily doses of 2000IU of supplemental Vitamin D, and possibly 5,000 IU, are now suggested.  
Tonsillectomy has long been considered a “cash cow” for throat surgeons.  For more than seven decades physicians have debated whether surgical removal of tonsils in young children is beneficial.  Clearly, many needless tonsillectomies continue to be performed.  A recent hypothesis links tonsillectomy with low levels of Vitamin D.  With the realization that modern medicine offers nothing in regards to prevention, Vitamin D therapy and prevention should be explored and practiced.