Help Carnivore destroyed my kidneys!!! pic.twitter.com/HmZVoT6KeE

— Dr Shawn Baker 🥩 (@SBakerMD) December 14, 2023

Creatinine was identified in 1886, different from Creatine.  creatinine has been measured in the blood, measured for well over 100 years, and you can estimate how much your kidneys are filtering.  When your creatinine goes up, it can be associated with kidney function going down and your GFR becoming lower and lower.  That GFR is an estimate based on the Creatinine level.  The problem with that estimate is that there are things that can affect creatinine that aren't necessarily pathological.  There are people with higher Creatinine who don't have any kidney disease.  And I'll use myself as a perfect example.  And how do I know that?  Because I've tested myself multiple times.  And I've tested it with confirmatory type testing to show that in my case with elevated Creatinine is not associated with any level of kidney dysfunction.  Let me explain.  

What can make your Creatinine go up?  Kidney failure, for sure.  Absolutely, absolutely.

What else can make your Creatinine go up?  Having a lot of muscle mass, being a muscular person in contrast to a little old lady that's frail and has little muscle will have really low Creatinine in many cases.  If you're a big guy, or a big gal with a lot of muscle, your Creatinine might be high.