Saturday, March 19, 2022

VISIBLE SIGNS ON THE SKIN OF INSULIN RESISTANCE

From NCBI

Acrochordons, also known as fibroepithelial polyps, skin tags, or soft fibromas, are among the most common skin tumors [14]. They are a benign skin condition unusual before age 30 years, but highly prevalent thereafter, particularly in advanced age. In fact, after age 40, the frequency of skin tags is ~37% [11]. They are more common among women and overweight or obese patients; however, these also have a familial/genetic relationship. Recently, several studies have associated acrochordons to impaired glucose tolerance and diabetes [1518]. In 1976, Margolis et al. conducted one of the first studies and reported that 9.4% of 500 hospitalized patients had acrochordons, of which 72% had T2D, and suggested that acrochordons could be a risk factor for diabetes [19]

Clinically, these lesions are small, soft, slightly hyperpigmented tumors of variable size and characteristically pedunculated (see Fig. 1). Acrochordons are frequently multiple, but can appear as a single lesion. Intertriginous sites such as the neck, axillae and groin are the most common areas of presentation; however, they can appear in other areas such as the eyelids and inframammary creases [161821]. Typically these skin lesions are completely asymptomatic and may become painful because of irritation [22]. Differential diagnoses include melanocytic nevi, neurofibromas, and pedunculated seborrheic keratosis; conditions associated with skin tags include Gardner syndrome, Birt-Hogg-DubĂ© syndrome, and tuberous sclerosis, among others [1823].

TREATMENT

Treatment is more of a cosmetic than a clinical concern, and various methods are currently used. Electrosurgery and cryotherapy are among the most commonly used methods, yet a challenge of this technique is the difficulty of limiting the freezing zone exclusively to the soft fibroma [25]. Flat tweezers can be used instead, dipping them in the liquid nitrogen and grasping the skin tags with the cooled metal [25]. However, the most direct and simple approach is to simply excise them with sharp and good-quality scissors at the level of the surrounding skin. Lesions with a wide base might require local anesthesia; ferric subsulfate and aluminum chloride can be used for hemostasis (Table 1).

I've seen the skin condition, Acanthosis nigricans too often.


I had no idea that doctors haven't been testing for hyper-insulin levels.  You'd think they would.  Again, COVID has leaked all the negligence and incompetence in a healthcare system that we weren't aware of.  And a word of caution, if you're ever asked to take a procedure and you know nothing about it, please don't just run to your doctor to get it.  Do nothing first.  Then proceed to learn more about the procedure.  Them and only then, once you've read and learned about the benefits and risks, the pros and cons, would it mean that you're acting on consent and not coercion.  Please, please, please, consider your future-self.  Be that butler to your future-self and ask him, what would my future-self want or need?  Too many folks simply surrender their critical thinking to doctors.  It's the worst type of helplessness I've ever witnessed
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