DR. ANTHONY CHAFFEE: it's just that high insulin suppresses autophagy and it suppresses all these other functions in your body. It suppresses the formation of ketones, forcing energy into cells; it doesn't allow them to come out of cells.

When you fast you just stop eating but you also just stop eating carbs.  And then your insulin comes down and then you start opening up your metabolism.  So the thing is that insulin doesn't just affect sugar metabolism and your blood sugar levels even though the American Diabetes Association would like you to think that because they say, "your diabetes patience oh they don't have to restrict carbs.  Just make sure they take enough insulin so they keep their blood sugar down because blood sugar being high is actually directly damaging it's to you and it's really just harmful to your body.  That's why you need your blood sugar levels down.  It's very important to your body to keep it down.  That's why it raises your insulin.  So basically it's toxic to your body over a certain point. Your body responds to this toxin, the high blood sugar being a toxin, by trying to detoxify it by raising your insulin to get it down.  But the problem is insulin affects over 100 different processes in your body, like autophagy.  So it's not the "not eating" that's doing it, it's just that high insulin suppresses autophagy and it suppresses all these other functions in your body.  It suppresses the formation of ketones, forcing energy into cells; it doesn't allow them to come out of cells.  So when your insulin level is up, you can't start using your fat as energy.