SAMA HOOLE: What cholesterol actually does: Fills your brain (a quarter of your cholesterol sits there); Insulates your nerves (no cholesterol, no signal); Repairs every cell you have (it stiffens the walls)

Your liver makes around 1,000mg a day on purpose, because you cannot run without it. 

They named the most vital molecule you produce the villain, then sold you a pill to lower it. --Sama Hoole  

What people think cholesterol does:

- Clogs arteries

What cholesterol actually does:

- Fills your brain (a quarter of your cholesterol sits there)
- Insulates your nerves (no cholesterol, no signal)
- Builds your sex hormones (testosterone and oestrogen, straight from it)
-…

— Sama Hoole (@SamaHoole) July 22, 2026

What people think cholesterol does: - Clogs arteries What cholesterol actually does:

- Fills your brain (a quarter of your cholesterol sits there) - Insulates your nerves (no cholesterol, no signal) - Builds your sex hormones (testosterone and oestrogen, straight from it) - Becomes vitamin D (sunlight turns it into the hormone in your skin) - Makes the bile that digests your fat (and unlocks vitamins A, D, E, K) - Runs your stress response (cortisol is built from it too) - Repairs every cell you have (it stiffens the walls)

Your liver makes around 1,000mg a day on purpose, because you cannot run without it.

They named the most vital molecule you produce the villain, then sold you a pill to lower it.