SAMA HOOLE: Pork fat is typically around 15-20% linoleic acid. Poultry is 20%. Grain-finished beef is just 3.3%. Grass-finished beef is 1.1%.

@samahoole The points above are excellent. As noted, since pigs and chickens have a single stomachs, what they eat translates directly to the meat and especially the fat. So if they are fed soy and corn (most are), they load up of glyphosates and linoleic acid can take 7 years…

— Paul (@pmfast) October 11, 2025

PAUL SALADINO: Seed oils accumulate in some membranes, and we can't get rid of it. Probably causes increased permeability of membranes, it accumulates in mitochondrial membranes

Costco Animal-Based Grocery Haul pic.twitter.com/fRyY6bgL20

— Paul Saladino, MD (@paulsaladinomd) September 6, 2024

My problem with most pork is that it's fed grains, corn, and soy and that corn and soy are very high in linoleic acid and pigs and chickens can't get rid of that linoleic acid, which means the fat of pigs and the fat of chickens fed corn and soy ends up much higher in linoleic acid than the corresponding fat of a wild pig or a wild chicken.  And wild chickens and wild pigs, the amount of linoleic acid is around 5% or 6%, but in domesticated chickens and pigs, you're looking at 15% or 16% linoleic acid.  And excess linoleic acid is the polyunsaturated fatty acid found in seed oils that I'm very worried about for a variety of reasons.  

Learn more about seed oils from Saladino through the podcasts he's done with Georgy Dinkov, Tucker Goodrich, and Jeff Nobbs.  Lots of reasons why seed oils and linoleic acid in seed oils harm humans.  It accumulates in some membranes, and we can't get rid of it.  Probably causes increased permeability of membranes, it accumulates in mitochondrial membranes in the cardiolipin, causing problems with the electron transport chain.  Leads to increased oxidation of LDL, increased oxidized LDL, and has been shown in randomized controlled studies, like the Minnesota Coronary, which is a long study with over 9,000 participants to be linked directly in that randomized controlled trial to higher rates of coronary heart disease, which makes sense when you realize that linoleic acid gets into the LDL particles and causes increased oxidation, etc. 

Will never forget the first time I ate food that included Canola oil.  My heart flipped inside my chest.  Shocked the hell out of me. 

Thanks to Joshua Booth for the above chart.  

Dr. Michael Eades on Obesity

9:31  The chart where Eades shows the fats consumed starting in 1971, he states that that is when the population began eating more vegetable oils.  We used to consume animal fats on a regular basis, lard.  Now we’re consuming vegetable oils.  I was shocked at the level of consumption of soy oil.  

9:55  He mentions the Economic Research Service, or ERS.  

10:45  He shows the decline in beef consumption. 

11:05  To explain the increase in vegetable oils and the decrease in the consumption of beef, he points to two reasons:  one, people are eating out more.  And when you eat out, you lose all control over what you eat.  He says you may order a steak and some sauteed asparagus, but you don't know what they sauteed it in.  [I think of this every time and it is one of the reasons why eating out, though sometimes necessary, is more and more disappointing.]  And you don't know what they seared the steak in.  When he was a kid, he says he never went to a restaurant until he was in the 7th grade other than when his family was traveling somewhere.  Other than that, every meal was at home.  We prepared at home.  Now, half the people eat out and lose far too much control over what they eat.  None of us know what any of this stuff is cooked in.  

On a side note, I ate a Panda Inn chain in Denver, and my stomach flipped in knots.  It was so bad that I called the restaurant to ask what oils they used to cook their foods in.  I was surprised that they told me: it was soybean oil, which sounded harmless enough and ubiquitous enough to me.  But I did learn that soybean oil is more fat-generating and diabetes-generating than coconut oil or fructose.

12:15  He cites a time when he went undercover as a chef at a chain restaurant to find out what kind of oils they use in their cooking.  And what he found was that they use Canola Oil, the most ubiquitous [because it's tasteless--neutral aromas] oil in outdoor dining and Soybean Salad Oil, and that's what they cook EVERYTHING in: steak, fish, burgers, French Fries.  When you order a salad with olive oil and vinegar, he says that you don't know if that olive oil hasn't been adulterated because of a huge problem with Olive Oil adulteration right now.  And B, that's a little tiny bit of olive oil, while the rest of your meal is slathered in Soybean Oil.  Even at stores, check the ingredients on package-wrapped sandwiches, crackers, or pastries.  You will find Canola Oil everywhere.  By the way, there is no plant called Canola.  Canola is a compound noun: it combines Canada with oil, hence, Canola.  Canola Oil has 32% Linoleic Acid.  Soybean Oil has 61% Linoleic Oil.  So the more we eat out, the more oils we get. And we're getting a pernicious oil: that's linoleic oil that contains linoleic acid.  What's the hazard of Linoleic Acid, you ask?

13:33  Stephen J. Guyenet, PhD .  Looks like he was on the Joe Rogan Experience back in March 2019, where he also provided his references to the great Gary Taubes.  

That Linoleic Acid Chart, 1961-2008, and how it contributes to subcutaneous body fat, compiled by Guyenet and Susan Carlson, 2015, can be found here.  Find more scholarly articles by Stephan Guyenet, Ph.D here.  Polyunsaturated Fatty Acids, PUFAs.

15:45  After 1980, our attitudes toward saturated fats changed.  We were told to be scared of it.  And because we were frightened by it, we've gone along with all of these guidelines to avoid saturated fats.  

16:05  Graph.  The blue-green lines are the things that we've been told to eat more of, and in the red are those things we've been told to eat less of. 

Eat more vegetables, fruits, grains, vegetable oils.  Eat fewer meats, eggs, whole milk, animal fats, butter.  From 1971 to 2011, there's been about a 20.5% decrease in the consumption of saturated fat.  

Changes since 1980, Linoleic Acid has gone way, way up.  Saturated fat has gone down and our calories, primarily, the carbohydrate calories have gone up.  So it's kind of the perfect storm:

1.  Wholesale adoption of vegetable oils.  

2.  Increased consumption of refined carbs. 

3.  The demonization of saturated fat.  

Hypothesizes that linoleic acid promotes obesity.  How does it promote obesity?  What's the mechanism?

18:00  Saturated fats protect against obesity.  In addition, the CI  [Carbohydrate + Insulin] Hypothesis is important.  

19:55  Petro Dobromylskyj's site, Hyperlipid.  

21:38  Food > ATP > gives us Life.  We eat food and break it down to high-energy electrons, or ATP, which is the currency of life.  Now we do all this in the mitochondria.  

26:30  Thousands of mitochondria in each cell, and you have billions of cells.  150 revolutions per second, and with each revolution they're cranking off an ATP.  They can churn out your body weight in ATP daily.  One can make 195 pounds of ATP.  That is phenomenal. 

28:35  We all want to increase our mitochondria and our mitochondria biosynthesis.  We can do this by eating right and exercising.  Great paper by Nick Lane, who has written the book, Power, Sex, and Suicide, 2018.

29:20  Hydrogen peroxide creates local insulin resistance at the cellular level.  Now, I am not talking about total body insulin resistance.  This can be protective of excess nutrients going into the cells from over-eating.  And it's one way the cells have to prevent taking in too much stuff that they don't want.