Curcumin is the Indian spice Tumeric.
Dr. Barry Sears says,
NAC is a hydrophobic derivative of amino acid cysteine. It is only this hydrophobic derivative that can cross the blood brain barrier to enter into the brain. Other hydrophobic polyphenols, such as curcumin, can also do this. This is why high dietary intakes of curcumin are related to reduced incidence of Alzheimer's.
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