When considering the potential benefits of NMN, you have to read the safety data, and there isn't much to date. However. Reading about what you may be considering to put in your body is a must. https://t.co/nr3u4Vfsvq
— DCGreenZone1 (@DCGreenZone) September 25, 2022
Some promising benefits from NMN.
Administration of NMN also can restore gene expression linked to circadian rhythm, inflammatory response and oxidative stress, and improve hepatic insulin sensitivity, partially by SIRT1 activation.
See the table at the end of this sentence for a list of benefits from NMN: Table 1.
NMN supplementation was capable of restoring NAD+ levels by threefold:
De Picciotto et al. [29] found that NMN supplementation was capable of restoring NAD+ levels (by threefold), vascular SIRT1 activity, maximum carotid artery endothelium‐dependent dilation, and nitric oxide‐mediated carotid artery endothelium‐dependent dilation in mice. Kawamura et al. [30] have reported that NMN retained in animals for longer period than nicotinamide. NMN resulted in a higher yield of NAD+ (80 nmol/g of liver tissue) in salvage biosynthesis pathway activating higher response of SIRT1 than nicotinamide.
And the list goes on:
Mills et al. [10] found that devoid of any apparent deleterious effect or toxicity,
NMN effectively suppressed aging-induced body weight gain
ameliorated eye dysfunction in mice.
maintained healthy plasma lipid profile, insulin sensitivity, physical activity, energy metabolism and other physiopathologies.
NMN supplementation averted alterations in age-associated gene expression in main metabolic organs, while enhancing mito-nuclear protein imbalance and mitochondrial oxidative metabolism in skeletal muscles.
NMN supplementation restored reduced contents of renal protective molecule, SIRT1 and its cofactor, NAD+. The heightened NAD+ and SIRT1 levels in kidneys of aged mice protected aged kidneys from both ischemia–reperfusion- and cisplatin-induced acute kidney injuries.This brand came recommended from a friend on Twitter.
