"choline pathway is a prime part of the disease mechanism and it is a good idea to keep the physiology in good shape."

No surprise given where S acts - PDE4s.
Last sentence of the abstract:
"...a range of important functions in the brain ... as a therapeutic target for a diverse collection of indications, such as, SCHIZOPHRENIA, neuroinflammation, & COGNITIVE FUNCTION."  https://t.co/FmJbb1kvlY

— Frank J. Herrmann - theFree gONE almost (@4141245879freun) April 27, 2022