Wednesday, June 26, 2024

Jesse Gelsinger Case, 1999 

17-year-old Jesse Gelsinger suffered from the genetic metabolic disease called orinthe transcarbamylase OTC deficiency this prevents the body from breaking down ammonia a metabolic waste product unless a person's diet is immediately adjusted and monitored throughout their life they will die soon after birth.

Although gel singer had controlled his OTC well he volunteered for a genetic therapy experiment in hopes of helping infants with a more severe form of the metabolic disorder he had a negative reaction to the treatment caused by severe immune response to the virus Vector used to deliver the corrective gene and died.

Three ethical issues with regard to gene therapy emerge from the Gelsinger case one should a relatively healthy adult volunteer with OTC have been used as a volunteer rather than newborns that were very sick too Gelsinger was told that the treatment was relatively safe however it emerged that past research subjects and experimental animals had become sick from the treatment was there adequate informed consent with regard to the risks three the lead doctor and institution had financial interest in the development of the treatment that was used if it had been successful they would have been well positioned to make a lot of money should researchers and research Institutes have a stake in clinical trials?

Wikipedia provides context on Jesse Gelsinger, 

Jesse Gelsinger (June 18, 1981 – September 17, 1999) was the first person publicly identified as having died in a clinical trial for gene therapy. Gelsinger suffered from ornithine transcarbamylase deficiency, an X-linked genetic disease of the liver, the symptoms of which include an inability to metabolize ammonia – a byproduct of protein breakdown. The disease is usually fatal at birth, but Gelsinger had a milder form of the disease, in which the ornithine transcarbamylase gene is mutated in only part of the patient's cells, a condition known as somatic mosaicism. As his deficiency was partial, Gelsinger managed to survive on a restricted diet and special medications.

AARON SIRI: "Everybody here is saying they're safe...Then there should be no reason to continue giving those companies the immunity to liability for injuries if they are safe, as has been advocated . . ."

DEMOCRACY IN ACTION: groups get together . . . officials then grinfu*k them for an hour and send them on their way . . .

Naomi Wolf is the leader and CEO of Daily Clout.  Daily Clout hired a law firm, John Howard's law firm, to file a letter with the Department of Justice which they sent at the beginning of July asking the Department of Justice to investigate the things that Daily Clout has found about how Pfizer conduct the clinical trials or the things that where presented to the public as clinical trials which way now know were not actually clinical trials.  They were fraudulent they were a pre tents intended only two convince people that clinical trials were happening when in fact they were not

Tuesday, June 25, 2024

Anatomy of the Colon


A must-watch and a must-listen. 

Your colon's health is not only about poop.  What else happens?

Large and Small Intestines.  The bowel is about 5 feet.  The intestinal tract is where you digest food above, and the small intestines are approximately 23 feet.  30 feet from mouth to anus. 

Pay attention to the graph on your colon.  Notice the major aorta in all the veins that attach to the colon walls.  Why is that vitally important?  

Because when you have poop stuck in your colon, you are technically poisoning yourself with the toxic substances sitting in your bowel.  And I just showed you all the blood attached, all the veins and the arteries, so all the toxins--skatole, cresol, indole, phenol, and the permeability of your wall.  All of these things are affected by stools sitting in that bowel and directly poisoning your blood.  And don't forget, your liver is cleansing that blood every 7 minutes.  

1:25  So what else about this blood supply?  What else do we know?  Picture of blood vessels and a major artery that's attached to the colon wall.  Well, look at this.  It's the Superior Mesenteric Vein that affects your lymph drainage and your nerve supply.  Nerves, meaning your sympathetic and parasympathetic nervous system.  That's your Vagus Nerve.  When you go to a chiropractor, they will adjust your Vagus Cranial Nerve.  It goes from the cranium all the way down the bowel. 

THE VAGUS NERVE
The Vegas nerve operates mainly within the parasympathetic nervous system linking major organ activity to the brain.  According to Medical news today it's four main functions are:
1)  SENSORY: providing sensory information from the throat heart lungs and abdomen.
2)  SPECIAL SENSORY: providing taste sensation behind the tongue.
3)  MOTOR: providing movement for neck muscles so you can swallow and speak.
4)  PARASYMPATHETIC:  responsible for your digestive tract respiration and heart rate functioning.

While the sympathetic nervous system controls the fight or flight response sending out stress releasing hormones like adrenaline and cortisol so you can take action.

The Vagus Nerve does the opposite, helping you get rid of stress and remain calm the more things you do to stimulate the Vagus Nerve the more relaxed you are and less stressed you'll feel.

GUESS WHAT?  It attaches right to your colon, and that's why people feel so much better after they've had a colonic

It's a mixed nerve. 
It's the longest, most widely distributed Cranial Nerve.  
It's distributed until the right 2/3 of the transverse colon.  
It contains Afferent, Motor, and Parasympathetic fibers.  

HOW CAN THIS TOTALLY AFFECT YOU?
It can affect you because it's responsible for your parasympathetic nervous system, which is the calming influence.  The sympathetic nervous system is stress, cortisol, you're running away from a bear . . . .  But this Vagus Nerve does the opposite.  It helps you get rid of stress and remain calm.  

2:35.  Here is your colon, and she's already shown us the major artery in the veins attached to that column wall which affects everything in your body because it's your blood.  It's like soil to a plant.  This is your blood directly affected by your colon.  But look at this these little green dots.  Those are your lymph nodes.  How important are your lymphs?  Well, basically your lymphs are your immune system.  The lymphs are like little trash cans that take out the garbage, and when they are full and when they don't move they get full of waste and matter.  And if they're attached here to this colon wall that's full of poop, you can see this is going to be a big problem.