Ketone Bodies Protect the Brain

Fascinating interview on the value of living in high altitudes. Denver and Reno are two cities with high altitude. What are the benefits? Weight loss. Better recovery from injury.

Show notes:

Sustained exposure to hypobaric hypoxia results in cachexia. Muscle breakdown releases amino acids, whilst hepatic ketogenesis converts fatty acids and some amino acids into ketone bodies. These act as metabolic substrates, but also as metabolic modulators eliciting protective effects against hypoxic injury. In this video, Andrew J. Murray and Hugh E. Montgomery explain their hypothesis and propose that hypoxia-induced cachexia is protective.

Read the article here: http://onlinelibrary.wiley.com/doi/10...