Monday, January 13, 2025

JOHN BEAUDOIN: mRNA should be banned [not suspended, not reviewed, not reconsidered, not revised] for use in healthy humans and animals.

Graying Hair? Relax in the Cold

Functional studies (herehere, and here) indicate that this allele produces an enzyme that has totally normal activity at 31 C (87.8 F), but at 37 C (98.6 F) it loses 75% of its copper-binding activity and at least 75% if not all of its enzymatic activity.  This indicates that the allele confers thermolability on the enzyme, making it intolerant to heat to the extent that normal body temperature impairs it. This is a common theme in enzymatic impairments.  31C is cold enough for hypothermia, and maintaining body temperature at that point is not a viable strategy to prevent hair graying.

Indeed, high body temperature helps all enzymatic reactions occur more effectively if the enzymes do not have impairments that make them thermolabile. For example, the wild-type allele for tyrosinase operates more effectively at 43 C (109.4 F) than at body temperature, but this is above the threshold of fever (41-42 C, 105.9-10.7.6F) that can cause brain damage and become life-threatening.

Maintaining supraphysiological copper concentrations is also not a viable strategy for preventing hair graying because high concentrations of free copper are toxic. In fact, they cause oxidative stress, which can lead to hydrogen peroxide production, which can destroy hair pigment and cause graying.
. . . 

This SNP is very common in people with European ancestry, where just under 40% of people are heterozygous and 7.6% are homozygous. It is not found in many Asians. It is found in American Blacks and Latin Americans, but not in African pygmies or Australian Aborigines, leading to speculation that it arose in Caucasians and spread to other groups through admixture.



MAY 2024: The DOD has its stamp all over Gaza

ALEX NEWMAN: If you know anything about the United Nations, there is no such thing as a peacekeeping role. It's a war-making role

Sunday, January 12, 2025

AZODICARBONAMIDE: It's yoga mat material. It's legal, and once again, illegal in Europe. It was in Wendy's. It was in McDonald's. Most of the companies didn't remove it, but she specifically was picking on Subway. She had a massive campaign. She got it out of Subway.

Food Babe is Vani Hart. 

Some background on Azodicarbonamide.  If this and other food additives don't force men and women back into the kitchen to make simple, nutritious food from scratch, I don't know what will.