Here is Hans Amato's Substack.
This remedy corroborates what two other doctors, Dr. Barry Sears and Dr. Andrew W. Saul, owner of the website, DoctorYourself, which may have been removed, have suggested in print to eat something before bed. Both suggested cheese since that would help with sleep.
Waking up 2-3 times a night to piss and thinking it's because you drank water before bed
— Hans Amato (@HansAmato) April 24, 2026
It's not the water
Your blood sugar is crashing at 1am, 3am, 5am. Each time it drops, your body dumps cortisol and adrenaline to bring it back up. Adrenaline wakes you up. Cortisol tells…
Waking up 2-3 times a night to piss and thinking it's because you drank water before bed It's not the water Your blood sugar is crashing at 1am, 3am, 5am. Each time it drops, your body dumps cortisol and adrenaline to bring it back up. Adrenaline wakes you up. Cortisol tells your kidneys to produce urine. You think you woke up because your bladder is full. Your bladder filled BECAUSE you woke up The urination is the symptom. The blood sugar crash is the cause This is why you pee barely anything each time. You get up, walk to the bathroom expecting a full bladder from all that water. Trickle. Back to bed. Awake again 2 hours later. Another trickle Because the bladder was never the issue. Your adrenals keep jolting you awake and your kidneys keep producing urine in response to the cortisol surge This is the same mechanism behind the 3am wakeup with the pounding heart. Same mechanism behind night sweats. Same mechanism behind waking up with racing thoughts and a sense of dread for no reason All blood sugar. All cortisol. All preventable What stops it: > Eat before bed. This is the single most important fix. A meal with protein, fat, and starch 1-2 hours before sleep. Sustains liver glycogen through the night so blood sugar doesn't crash. Rice + eggs + glass of milk. Potatoes + butter + meat. Something substantial. Not a handful of almonds > Stop undereating during the day. If total daily calories are too low, liver glycogen depletes by midnight regardless of what you eat before bed. Your body needs enough total fuel to make it through 8 hours without triggering an emergency response > Salt your evening meal. Sodium supports adrenal function. Low sodium at night means your adrenals are working harder to maintain blood pressure while you sleep. More cortisol output. More waking. > Magnesium glycinate 400mg before bed. Calms the nervous system. Supports GABA production. Reduces the cortisol reactivity that's waking you up. > Honey before bed. 1 tablespoon raw honey. Replenishes liver glycogen specifically. The liver uses glycogen to maintain blood sugar while you sleep. Honey tops it off. Stupid simple. Dramatically effective for a lot of people. > Check fasting insulin and fasting glucose together. If insulin is high and glucose is "normal," your body is working overtime to regulate blood sugar during the day. At night when the system relaxes, it loses control. The crashes happen. > Avoid alcohol before bed. Alcohol initially drops blood sugar then triggers a rebound spike and crash cycle through the night. The "I always sleep terribly when I drink" phenomenon is blood sugar chaos for 6 hours straight. Had a client. 36. Waking up 3-4 times every night for 2 years. Urologist said prostate was fine. Sleep study said no apnea. Prescribed Flomax anyway. He was eating his last meal at 6pm. Training at 7pm. Going to bed at 11pm. Five hours without food plus a glycogen-depleting workout right before a fast that lasts until morning. His liver was running out of glycogen by midnight. Cortisol alarm going off every 2 hours for the rest of the night. We added a real meal at 9pm. Bumped total daily calories by 400. Tablespoon of honey before bed. Magnesium. Slept through the night on day 4. First time in 2 years. His prostate was never the problem. His bladder was never the problem. He was starving in his sleep and his body kept hitting the fire alarm.
If you're getting up multiple times a night and peeing small amounts each time, eat more food and eat it closer to bed. That's usually the whole fix. DM me "REPORT" for the custom health report. Here's what you get: - full symptom and history mapping specific to you. - the most likely biological root causes behind what you're feeling. - exact labs to order and how to read the results yourself. - a prioritized protocol: what to fix, in what order, built around your body. Not a generic PDF. not a supplement list. a personalized breakdown of what's actually wrong and how to fix it The report your doctor would give you if he had 4 hours instead of 13 minutes.
