Wednesday, August 10, 2016

Dave Asprey, Creator of BulletProof Coffee (Fantastic Product!) Interviews Dr. Barry Sears, Creator of the Zone Diet

This is a long interview. It's good but it's long. Polyphenols are master sculptures of the gut.
Well, this point was interesting.  Asprey asks which is better--eating 2 pounds of green leafy vegetables or eating high fat meals?
Polyphenols in berries are more water soluble and so find their way into your blood stream better. Green leafy vegetables have less water solubility.  Sounds like they are better used for insoluble fiber than for their polyphenol effect.  The conundrum is that berries have a higher sugar content, so you can't eat a bunch.  Sears argues for concentrates extracted without the sugar content and without the inefficient solubility into your blood stream.  He is essentially recommending his products.

Alberto Viejo recommneds high amounts of polyphenols so your stress


Polyphenol has a half-life.  Their half life is measured in hours. The genes you're activating.  

The green coffee polyphenol are rich in polyphenols but very bitter. They have to be cooked and the polyphenols are released.  In nutrition, nobody's wrong, but often they're not completely right.

You need . . .

Adequate amount of protein [i.e., amino acids] in a day.
Adequate amounts of essential fats. 
Adequate levels of polyphenols.  Essential to manage inflammation.

So you have to have adequate amounts in the right balance to maintain insulin in a zone.  

The fat will have no effect on insulin. Medium-chain triglycerides developed at Harvard Medical School back in the 80s were used for treating burn victims?  Water soluble.  Enter into the blood stream through the portal vein, go directly to the liver and metabolized there on the spot and wipe out stores of glycogen.  Get ketosis very quickly.  Can no longer maintain blood sugar levels for the brain.  


The brain is the only organ that can use energy.  Wow!  Never heard that before.  


Central nutrients Get them all together with the least amount of calories but with the best hormonal response.  Food affects hormones and the expression of our genes.  It's really gene therapy in our kitchen.


Start-ups using time and money to say that it tastes good.


FDA has made it clear: you can make drug-like claims if they're supported by good, clinical research.  Rat studies from China is not "good, clinical research."  You've got to use people.  


Foods and drugs have therapeutic zones, above which the food/drug is toxic, below which the food/drug is ineffective.


Sears claims that the Zone Diet book was really written for cardiologists. 


It's an inflammation management diet, not a weight control diet, althought it will control your weight.  


Excessive Omega 6 from soy and cheese.  I love cheese!  Is this my problem?  


Essential fatty acids are essential because they control powerful hormones in our bodies, called eicosanoids.  Eicosanoids are 

prostaglandins and related compounds.  Most are produced from arachidonic acid, a 20-carbon polyunsaturated fatty acid (5, 8,11, 14-eicosatetraaenoic acid.  The eicosanoids are considered "local hormones."  They have specific effects on target cells close to their site of formation.
A balance creates a nice homeostasis.  Our ability to produce Omega 6 fatty acids is monumental.  Every disease state is the result of Omega 6: obesity, diabetes, Alzheimer, cancer, etc.  When increase the levels of insulin we get an explosion of inflammation. We were ground zero with Omega 6 fatty acids.  Italian children are the fatest in Europe.  

People developed a fat trap, where the calories get into your fat cells and being trapped in your fat cells and not being released to make energy, like ATP.  Gaining weight while starving!!  Signicant change in their metabolism.  Constantly starving of energy. 


Fat cells are our swiss bank account.  Fat Trap caused by significant inflammation.  Not enough ATP, you either slow down or make more calories.  


Metabolism: converting calories into energy.  If you're not hungry 5 hours after your meal, it means you've rectified your metabolism. 


            

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