CAFFEINE: not only helps to protect the BBB but is also useful against SARS-CoV-2, Alzheimer's Disease [AD], and Parkinson's Disease [PD]

Friday Hope: Caffeine: Blood-Brain Barrier Protection and SARS-CoV-2 Therapeutic Properties https://t.co/DTXE9IDUey

— St. Michael, the Archangel (@aveng_angel) February 17, 2024

Okay, so COVID-19 as well as the COVID-19 gene therapy shots disrupt the blood-brain barrier, BBB.  Well, then isn't there some food, some therapeutic that would protect the blood-brain barrier?  Yes, there is.  Caffeine.  That's right, your morning cup of joe.

Given the recent study showing that SARS-CoV-2 disrupts the Blood-Brain Barrier (BBB), I stated that I would search for therapeutics that help to protect the BBB and ward against neurodegenerative diseases. I found one such therapeutic that not only helps to protect the BBB but is also useful against SARS-CoV-2. This is none other than Caffeine. 

Find sources here.

CAFFEINE PROTECTS AGAINST ALZHEIMER'S DISEASE, AD

Caffeine protects the integrity of the blood-brain barrier.

Recent epidemiological and experimental studies indicate that caffeine, when administered chronically, has beneficial effects against a number of acute and chronic neurological disorders including stroke, AD, and PD. For AD, the protective effects of caffeine have been observed in humans as well as in animal models of this neurodegenerative disorder. Epidemiologically, chronic ingestion of caffeine conferred protective effects against AD and a retrospective study showed that caffeine intake is associated with a significantly lower risk for AD. Prospective studies confirmed the above findings by showing that chronic caffeine intake improved memory and cognitive function in normal aged individuals as well as in AD patients. Subsequently, experimental studies conducted using animal models of AD noted that caffeine improved cognitive abilities, reduced Aβ production, and stabilized BBB integrity. Thus, caffeine and drugs like caffeine might be part of any regimen intended to prevent, delay, and/or treat AD.

BBB PROTECTING ASPECT OF CAFFEINE MAY ALSO TREAT PARKINSON'S SYMPTOMS

epidemiologic studies demonstrated that caffeine when administered chronically decreased the risk of developing PD. Experimental studies confirmed and extended the epidemiological findings by showing that caffeine was neuroprotective against the loss of dopaminergic neurons that occurs in the substantial nigra of MPTP-treated mice. Thus, current evidence strongly suggests that caffeine is a promising agent in the prevention and/or treatment of PD.

 

SERIOUS HEALTH WARNING: COFFEE INCREASES CATECHOLAMINES. IF YOU'VE TAKEN A VAX, MUST GREATLY REDUCE YOUR COFFEE CONSUMPTION

Beware, morning COFFEE cause you to die suddenly...if you got the covid vax/booster. Catecholamines are the cause of sudden death among jabbed athletes...serious health warning, you can no longer have coffee ever after the jab.   pic.twitter.com/RdN8W1v3QA

— Dr. Hachi (@DrHachi3) March 27, 2022

This is not new.  Coffee has already had the ability strip your body of essential B vitamins from fat-soluble B1 to B9 to nerve-regenerating B12.  Bill Sardi wrote about this https://knowledgeofhealth.com/not-covid/.

And fat-soluble B1 is the answer.  Coffee leeches B1 from your system.  You need B1, not coffee.  https://www.lewrockwell.com/2019/06/bill-sardi/falling-through-the-cracks-in-modern-medicine/.

Here are other concerns about Catecholamines. 

Low dopamine affects the ability to focus and think, while high dopamine causes an overload on the brain’s ability to process information. Here are some of the important functions of dopamine which are all crucial to children with neurodevelopmental disorders:

Memory

Cognitive functioning

Clarity

Attention

Focus

Motivation

Motor control

Movement

Appetite

Problem-solving

Emotional responses

Sensitivity

Processing information

Relaying information

Perception of change

Posture

ANTI-DOPAMINE RECEPTOR ANTIBODIES

Children with autism, ADHD,  Sensory Processing Disorder,  Lyme disease, PANS/PANDAS, OCD, ODD or mood disorders may have pathogenic infections that have crossed the blood-brain barrier because of traumatic brain injury or exposure to EMFs (electromagnetic field), toxins or antibiotics. Cross-reactive antibodies created in response to these pathogenic microbes attack the dopamine receptors in the basal ganglia of the brain, causing a fluctuation in dopamine, which results in OCD, tics and other neuropsychiatric symptoms. This is sometimes called autoimmune-mediated basal ganglia dysfunction.

People can have a leaky gut and a leaky brain where not so much that things leak from the brain but that they leak or seep into the brain.  Dr. Walter H. Backes of Maastricht University Medical Center writes 

Blood-brain barrier leakage means that the brain has lost its protective means, the stability of brain cells is disrupted and the environment in which nerve cells interact becomes ill-conditioned. These mechanisms could eventually lead to dysfunction in the brain.”

I know for a fact that a high-grade fish oils, beef, animal fat, grass-fed butter go a long way at repairing the BBB, blood brain barrier.

ANY AMOUNT OF COFFEE IN YOUR DAY STAVES OFF MORBIDITY

I know you love the taste of coffee.  If it's not the taste, then it's the memories, and to be more specific, it is the times that you drink or the people you've shared a cup with that you quietly and wordlessly enjoy the aroma, the warmth, and that special memory.  Few things in the world can produce such an effect.  But know, too, that coffee is a diuretic.  What that means is that you're going eliminate fluids from your body, fluids that contain certain health-preserving nutrients.  So it's a trade-off.  Aren't most things? 

O, Headlines!

CNBC: “Drinking as many as eight cups of coffee a day could help you live longer, study says”

Time:  “Drinking Coffee May Help You Live Longer, Study Says”

Boston Globe: “Drinking Up to 8 Cups of Coffee Per Day Might Help You Live Longer, Study Says”

South China Morning Post: “Coffee May Help You Live Longer, Even If You Drink Eight Cups a Day, New Study Shows”

Science Alert: “8 Coffees a Day Means a Longer Life Than No Coffee, According to a 10-Year Study”

The burst of reports on the benefits of coffee feels more like a campaign than a newsworthy news story.  First, they’re not health reports.  Without a context, the headlines, like all headlines, are fantastic.  They are slogans in a campaign, like “Drink coffee, live longer.”  Or “Cups of Coffee helps you live longer.”  So coffee is slowly but consistently being pitched as a health or age-defying concoction with the added benefit of a caffeine jolt that restores you to youthful energies.  The coffee industry is hopped up on its own product.  It’s salesmanship not on caffeine but on steroids.  And we’ve even heard from Dave Asprey, the Bulletproof Coffee guru.  I have no doubt that if you add fat—butter or coconut oil—to your coffee that you will feel a bigger and longer-lasting boost of energy than if you drank just a cup of black coffee.  So a new report was published by the The reporting is bad that to get to the truth of what the conclusions to the actual study said is like stepping through a minefield.  Here are the findings reported at JAMA, the Journal of American Medical Association: 

Findings  This large prospective cohort study of a half million people found inverse associations for coffee drinking with mortality, including among participants drinking 1 up to 8 or more cups per day. No differences were observed in analyses that were stratified by genetic polymorphisms affecting caffeine metabolism.

The headlines above poorly represent the details of the findings in the British study.  You need to drink 8 cups of coffee to get the benefits.  Any amount of coffee per day staves off morbidity regardless of if a person metabolizes coffee quickly or slowly.  The states that participants consumed a range of coffee from 1 to 8 cups.  So any amount of coffee that you drink each day has protective effects against morbidity.  Morbidity is illness or near-death disease.  So all that the study shows is that coffee keeps a diseased person alive longer.  So in this light, coffee is beneficial.  It gives people with states of morbidity more time.  

Conclusions and Relevance  Coffee drinking was inversely associated with mortality, including among those drinking 8 or more cups per day and those with genetic polymorphisms indicating slower or faster caffeine metabolism. These findings suggest the importance of noncaffeine constituents in the coffee-mortality association and provide further reassurance that coffee drinking can be a part of a healthy diet.

Put in this context, coffee is not the elixir that the industry is trying to make it out to be.  The anti-aging and health market is booming and it is lucrative.  Have you seen the prices of some of these high-end products?  Try finding a boutique, quality vitamin for under $50; hell, under $100.  So by positioning itself as a healthful elixir, the coffee industry is sure to gain an increase in market share of the health and health food industry.  

The article at MSNBC starts like this.  

Drinking coffee could boost your chances of a longer life, research shows, even for those who consume as many as eight cups a day. 

Note the reference to excessive coffee drinking.  Why are 8 cups a health hazard for some, while drinking a few cups evidently healthy?  Long-term coffee consumption lowers the risk of death.

In a study of around half-a-million British adults, coffee drinkers were found to have a slightly lower risk of death over a 10-year follow-up period than non-coffee drinkers.

And it doesn't matter the form of coffee, whether it's instant or brewed ground coffee.  The interesting part of the study that I liked was that benefits were experienced in folks with metabolic problems.  That's kind of powerful news.  

The apparent longevity boost comes as yet another piece of good news for coffee lovers, with health benefits recorded in drinkers of instant, ground and decaffeinated coffee. The study is also the first of its kind to suggest health benefits in people with so-called genetic glitches affecting how their bodies react to caffeine.

My one concern and one that is even noted by the study is that coffee is not the health elixir that it's being reported as.  Yes, it contains anti-oxidants.  And, yes, as a diuretic it can help to leach excessive, unbound iron in your blood.  But as a diuretic, it not only leaches unbound iron, which is a healthy function particularly in men over 40, but it also leaches vitamins B, C, and others.  If one is a regular coffee drinker, it is important to take magnesium, for coffee hardens blood vessels; the magnesium helps to relax them.  So coffee can block the metabolism of certain foods and vitamins.  Coffee is a chelator.  So if someone wants to rid themselves of excess unbound iron, coffee is not a bad way to go.  But know, too, that you'll be interfering with nutrient absorption from foods and vitamins.  

Health experts warned people should not start drinking coffee, or increasing their intake, for medical reasons. They also warned too much coffee for women during pregnancy could be harmful.

Personally, I don't trust all of the government-sponsored health organizations, like JAMA or NCI, the American Cancer Society, and others.  It's always better to go with folks who are immersed in health supplements and very specific, highly targeted nutritional compounds to treat specific conditions.  You can do your own reading and should.  Your productive life is at stake.  Plus, there is so little accountability from doctors, so their incentive to do a good, professional job.  Take your health into your own hands.  

HEALTH BENEFITS

Researchers at the National Cancer Institute (NCI) used data from people taking part in a genetic study called the U.K. Biobank. The participants of that study volunteered to give blood and answer detailed health and lifestyle questions.

For the latest study, published Monday in the Journal of the American Medical Association’s JAMA Internal Medicine, NCI researchers analyzed information provided by approximately 500,000 people, who answered questions about coffee consumption, smoking and drinking habits, medical history and more. 

If you're going to drink coffee, you'll need to take nutritional supplements, all of them--A, B, C, D, E, and minerals like zinc, magnesium, and a little calcium.  The reason is that coffee leaches nutrients, so be forewarned.  Bill Sardi explains this process:  

The problem of thiamin deficiency may be traced to another daily practice, the consumption of coffee, tea or beer. Many millions of people consume coffee or tea at the same time they take their morning multivitamin. What's the problem with tea or coffee? They contain tannins (bitter parts) that alter vitamin B1 and render it useless. Sulfite preservatives, as found in wine, are another antagonist to B1. Alcohol also interferes with B1 absorption. In fact, about 30-80% of alcohol users have low circulating levels of B1. The lesson here is not to take vitamin B1 pills with coffee, tea or alcohol. 

Another author, SFGate, argues the same point. 

Coffee, tea, cola and other caffeine-containing drinks and foods have a mildly diuretic effect on your body. Moderate consumption of caffeine should present no problem for people with well-balanced diets that supply all the nutrients their bodies need to function properly. However, because B vitamins are water soluble and are flushed out of the body through excretion, heavy caffeine users may need to supplement with B-complex vitamins to compensate for nutrients lost through diuresis. Naturopathic doctor Linda Page, author of “Healthy Healing,” says excessive caffeine consumption hits your body’s stores of thiamine particularly hard. 

Preceding those remarks, the SFGate author explains that 

B vitamins play a key role in converting the foods you eat into energy, but unhealthy diet choices, too much stress and certain drugs can rob you of their vital benefits. Although they are available in wide array of animal- and plant-based foods, B vitamins are water soluble and cannot be stored in body tissue. As a consequence, you must renew your supply each day and avoid the forces that can rapidly deplete them from your body. 

A poor diet AND caffeine strip your body of these important nutrients.  So you'll want to ask yourself, how can coffee, a diuretic that leaches key nutrients from your body also extend life?  

COFFEE: DON'T WORRY ABOUT CANCER; WORRY ABOUT IT DEPLETING B1, THIAMINE

Well, don't expect to learn of the real value of food or their nutritional compounds from non-profits.  Starbucks, and other sellers inside California, has been ordered to post a warning that their coffee contains carcinogens.  Oh, brother.  This is terrible.  Whether coffee contains carcinogens or not is not why this is a terrible regulation.  What's terrible is that the customer may find a message on his cup that reads similar to the cigarette warning of:  

SURGEON GENERAL’S WARNING:

Smoking Causes Lung Cancer, Heart Disease, Emphysema, And May Complicate Pregnancy

What's dumb about it is that the warning itself is subliminal.  It's a message that the consumer inhales with each bite, sip, puff puff, or what have you.

Further, the compound that has been designated a carcinogen is acrylamide, a chemical used in the roasting process.  And the article does not go into what kinds of cancers what might get with acrylamide.  So there are no details.  

Thursday, March 29, 2018 07:53PM

LOS ANGELES (KABC) --

A judge ruled that Starbucks and other coffee sellers in California must provide a cancer warning on their products for customers.

A nonprofit group sued several companies that sell coffee, including Starbucks, coffee distributors and retailers in 2010.

The lawsuit claimed those companies violated state law, which requires them to warn consumers about chemicals in the roasting process that may cause cancer. One of those chemicals is acrylamide, which is a carcinogen.

Attorneys for about 90 companies said the chemical is present in the process, but that it's at harmless levels and is outweighed by the benefits of drinking a cup of coffee.

The ruling came despite eased concerns in recent years about the possible dangers of coffee, with some studies finding health benefits. In 2016, the International Agency for Research on Cancer--the cancer agency of the World Health Organization--moved coffee off its "possible carcinogen" list.

The Associated Press contributed to this report.

Coffee is a mixed bag nutritionally speaking.  It is a mild mineral chelator.  That can be good if someone already has cancer and they're trying to reduce absorption to more heavy minerals, like iron, mercury, and calcium.  Coffee is good for your vision.  So it has a couple of benefits.  But if someone is an addictive drinker of coffee, like I was, it can deplete B vitamins to the point that you'll actually feel tired.  That's not good.  But again this only after a week or two of steady coffee drinking of 3 to 4 cups a day, depending on your current B vitamin status.  You may already be deficient in B vitamins adn then drinking coffee on a regular basis, well, then it's not good for you.  So it's not so much that the coffee is bad; it's that your body requires daily sustained amounts of B vitamins.  Get it?  Good.  Read Bill Sardi on this.  

The problem of thiamin deficiency may be traced to another daily practice, the consumption of coffee, tea or beer. Many millions of people consume coffee or tea at the same time they take their morning multivitamin. What's the problem with tea or coffee? They contain tannins (bitter parts) that alter vitamin B1 and render it useless. Sulfite preservatives, as found in wine, are another antagonist to B1. Alcohol also interferes with B1 absorption. In fact, about 30-80% of alcohol users have low circulating levels of B1. The lesson here is not to take vitamin B1 pills with coffee, tea or alcohol. 

Forget about cancer.  This is what you really have to worry about from your addicting consumption of coffee.  A cup or two per day may not be that bad, but be sure that you're taking B1 away from your coffee consumption.  

A policeman is flagged down by a 32-year-old woman at a park in Joliet, Illinois who says she can't remember who she is or how she got there. She is later found to be a mother of four children living in Jackson, Michigan. Her name is Amber. She has not recovered memory of her earlier life or what triggered her amnesia. Doctors are at a loss to know what caused this case of "global amnesia."

Marie is college educated, with a father who is a physician and mother who is a nurse, and she can't find anyone who can tell her why she is experiencing severe nausea and vomiting early in her first pregnancy. No one seems to know. Folk remedies are sought. Despite being the most common torment of pregnancy, the cause of morning sickness remains a mystery. Or is it?

Jim, a rock sculptor living near Ontario, California, looks like Indiana Jones in the movie Raiders Of The Lost Ark. Prop him up on a bar stool drinking down some brew and he would fit into any beer commercial. He is manly but has an unmanly and embarrassing problem. All of a sudden he can't seem to control his bowels. He is running to the bathroom all the time. His doctor says it is irritable bowel syndrome, a now common condition that forces sufferers to be closely tethered to bathrooms. A drug is prescribed that slows down gastric transit time but induces sleepiness, and can't be taken while driving. But what is the cause of his problem?

Jackie is out of work and living in Santa Fe, New Mexico and suffering with relentless pain that has been diagnosed as fibromyalgia. Doctors don't seem to have an answer as to what causes this problem. Inexplicably, a number of people with fibromyalgia report having the same problem as Jim the rock sculptor (above), irritable bowel. Are the two conditions linked in any way? An estimated 5 million Americans have fibromyalgia, some of them children.

Robert, an award-winning journalist, wakes up one morning with a slight weakness in his left leg. Then he begins to lose his ability to speak. He has to say "yes" or "no" by shifting his eyes. Doctors offer an experimental drug. For unexplained reasons, doctors delay treatment until Robert loses feeling throughout his body and is now permanently confined to a wheelchair. Doctors say Robert had a bout of Guillain Barré syndrome that never went into remission as most other cases do. Again, doctors have no idea of the cause of this progressive loss of nervous system control, some believing it is triggered by a virus.

Steve, age 35, had been suffering heart palpitations for years and finally was diagnosed with atrial fibrillation, a quivering heart muscle in the top chambers of the heart. Surgery and medication began to slowly help Steve regain his energy. Steve wonders if his children will inherit his problem. Despite successful treatment, neither surgery nor medication addresses the still unknown cause of atrial fibrillation. Millions of Americans, mostly men, face this same problem. Treatment consists of prescribing blood thinners to prevent a blood clot in the heart being thrown into the lungs or brain and controlled destruction of the heart muscle (ablation) itself. But what is its cause?

Martin, at age 56, first noticed could not keep up with his 70-year old brother in law when out hunting. He began to experience shortness of breath, fatigue, swelling in his ankles and a persistent cough. The diagnosis: heart failure. The cure: the implantation of a device in his chest that helps his heart pump blood. The device is credited with saving his life. More commonly heart failure is treated with a battery of drugs. But a recent study shows the drugs are of negligible value. 

Coffee Is Rich in Polyphenols But Spikes Insulin

Coffee is a stimulant whose breakdown products spike insulin. But coffee has a dark color and that means it is rich in polyphenols or anti-oxidants. Remember, any color in any that occurs naturally is rich in polyphenols. Blueberries, cherries, raspberries, all rich in polyphenols.  Unsweetened chocolate--rich in polyphenols.  Coffee is rich in polyphenols but its breakdown products do spike insulin.  So you need to make the call whether it is worth it.  I like it, so, yes, to me, it is worth it.

Decaffeinated coffee is soaked in methelyne chloride.  The same stuff is used to soak your laundry at the laundromat when they dry clean it.  This pulls out the caffeine.  Then they try to drive off all of the methelyne chloride and then add the flavors back.  What!  That doesn't make sense. This method may be the cheapest method to extract the caffeine.  There are more expensive, time-consuming methods that uses hot water to extract caffeine.  Caffeine is more water-soluble than the polyphenols are. 

He says that most people don't do well with coffee--caffeinated or de-caffeinated.  Hmm. 

He recommends teas, particularly green tea.  He cites the green color in green tea as possessing a lot of polyphenols.  But all teas have color. I haven't come across a single tea in my life that doesn't have color.  Unless you're talking about plain hot water; if so, that's not tea.  He explains that black tea (there's your colors) are fermented green teas. Didn't know that. He says that black teas, like Lipton teas and others, have only 1/10 the amount of polyphenols that green has.  Again, not heard that before. It's why green tea tastes more bitter than black tea.  Interesting.  So the bitterness of a food also indicates a higher concentration of polyphenols? Apparently so if you're comparing chocolates.

To knock out the bitter taste of green tea, he recommneds adding lemon or sugar.  He points out that tea has about half the caffeine as coffee. One cup of green tea will contain about 600 ORAC units. The higher the units, the greater concentration of polyphenols.  Dr. Mercola explains what polyphenols are and why they're important:  

Polyphenols are phytochemicals, meaning compounds found abundantly in natural plant food sources that have antioxidant properties. There are over 8,000 identified polyphenols found in foods such as tea, wine, chocolates, fruits, vegetables, and extra virgin olive oil, just to name a few.

Polyphenols play an important role in maintaining your health and wellness.  Antioxidants as a group help protect the cells in your body from free radical damage, thereby controlling the rate at which you age.

If your body does not get adequate protection, free radicals can become rampant, causing your cells to perform poorly. This can lead to tissue degradation and put you at risk of diseases such as heart disease, cancer, and Alzheimer’s disease, for example.

Healthwise, seems that coffee is best when fully caffeinated and enjoyed with a meal to minimize the spike in inuslin.  So enjoy a cup today.