PAUL STAMETS: . . . researchers found that comprehensive lifestyle changes including introducing 4 daily capsules of Lion’s Mane mushroom mycelium led to significant improvements in cognitive function and memory in people with mild Alzheimer’s.

Fungi for the win! https://t.co/IlDVtp1BQR

— Kevin McKernan (@Kevin_McKernan) July 31, 2025

A new clinical trial published in PNAS, shows that comprehensive lifestyle changes including diet, movement, stress reduction, and adding Lion’s Mane mushroom mycelium can lead to improvements in brain function for people with early-stage Alzheimer’s.

In a randomized clinical trial published in Alzheimer’s Research & Therapy, researchers found that comprehensive lifestyle changes including introducing 4 daily capsules of Lion’s Mane mushroom mycelium led to significant improvements in cognitive function and memory in people with mild Alzheimer’s. This is a promising development in the field of functional medicine and neuro-regeneration. It confirms that mushrooms like Lion’s Mane support brain health in profound ways and work best when paired with whole-body wellness. Learn more: https://cnn.com/2025/07/29/health/ornish-early-alzheimers-study-wellness. 

Effects of intensive lifestyle changes on the progression of mild cognitive impairment or early dementia due to Alzheimer’s disease: a randomized, controlled clinical trial.

Lion's Mane Mushroom.