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Showing posts with label Prions. Show all posts
Showing posts with label Prions. Show all posts
Friday, April 19, 2024
WALTER M. CHESTNUT: Friday Hope: Curcumin II: Inhibiting SARS-CoV-2, its Spike Protein… and PRIONS
Sunday, January 9, 2022
mRNA vaccines contain the genetic code to make spike protein. The RNA is carefully engineered to resist breakdown (PEGylated)
The va☠️☠️worse than glyphosate!
— Own Silver to say: I do not comply ! Steve_AG WSS (@RightsSpiritual) January 8, 2022
Dr Seneff, known for her ground breaking research on glyphosate, gives talk on the cl0t sh0t!
The spike protein as a prion. https://t.co/6bjPkBZMOb
Seneff is speaking with the World Council for Health.
mRNA vaccines contain the genetic code to make spike protein. The RNA is carefully engineered to resist breakdown (PEGylated)
all of the uridines are replaced
with 1-methyl-pseudouridine (m1Y)
the mRNA is incorporated into a
lipid particle that simulates a human LDL particle.
A synthetic cationic (positively
charged) lipid is added to act as an adjuvant—very toxic to the cells.
The “humanized” mRNA is a stealth entry system for the massive production of spike proteins.
THE BIG PICTURE
A natural infection starts in the
nose and lungs and never makes it into general circulation if the immune system
is healthy.
Injection of spike mRNA
nanoparticles into deltoid muscle bypasses mucosal and vascular barriers.
Immune cells take up mRNA
nanoparticles and carry them into the lymph system, ultimately into the spleen. It’s all been set up so that it can’t be
controlled or shut down. The vaccines
are very successful in producing a huge antibody response.
Immune cells in the spleen release
large quantities of spike protein displayed on the surface of exosomes.
These exosomes disperse throughout
the body, but, especially travel to the brain along nerve fibers to deliver the
toxic prion-like spike protein to neurons and the brain.
The inflammatory response in the brain
induces neurological damage.
“Is COVID-19 a Perfect Storm for
Parkinson’s Disease?” Patrik Brundin,
Avindra Nath, and J. David Beckham.
Loss of smell is a common early
symptom of Parkinson’s and of COVID-19.
The virus can gain access to the brain
along nerve fibers.
Along
the olfactory nerve, the virus can gain access to the brain.
Vagus
nerve
Neuroinvasion of SARS-COV-2 could
upregulate a-synuclein:
High
levels of a-synuclein lead to misfolding and toxicity.
Dopaminogenic neurons in substantia
nigra express high levels of the ACE2 receptor.
PARKINSON’S IS PRODUCED IN THE GUT
Parkinson’s disease often begins in
the gut as an immune reaction to prion-like proteins produced by pathogens.
The spike protein is a prion-like
protein.
It contains 6 glycine zippers (GxxxG)—a characteristic
signature of prions (The human prion protein contains 15, and amyloid-beta
(linked to Alzheimer’s disease) contains only 4.
Stressed immune cells in the
digestive tract and spleen upregulate a-synuclein and release it packages up in
exosomes, along with foreign misfolded proteins.
The exosomes travel along the vagus
nerve to the brain stem nuclei.
Damage to the substantia nigra
causes Parkinson’s disease.
The whole process can take years or
decades before symptoms appear.
S. Seneff and G. Nigh IJVTPR 2021;
2(1):38-79.
Paper from India: Ritu Mishra and Akhil C. Banerjea. Frontiers in Immunology 2021; 12:656700.
“SARS-CoV-2 Spike Activates Human
Microglia in the Brain via Exosomes Loaded with miRNAs.”
It transfected cells to DNA code to
make their own spike protein.
SARS-CoV-2 spike transfected cells
release a significant amount of exosomes loaded with microRNAs such as miR-148a
and miR-590.
MicroRNAs get internalized by human
microglia in the brain.
Induce
a strong inflammatory response.
These results uncover a bystander
pathway of SARS-CoV-2 mediated CNS [central nervous system] damage through
hyper-activation of human microglia
Exosomes will produce cells loaded
with miRNAs. These miRNAs are very
strong, controlling signaling molecules that will cause immune cells to produce
an inflammatory response. And so these
get internalized by these microglia in the brain. And this induces a strong inflammatory
response, which will lead to brain swelling, brain damage, and all these bad
things. To quote them, “These results
uncover a bystander pathway of SARS-CoV-2 mediated CNS [central nervous system]
damage through hyper-activation of human microglia.”
Figure 1. Marianna D’Anca et al. Frontiers Aging Neuroscience 28 August 2019;11:232.
The donor cell can be very far away from the recipient cell. And the donor cell would be that all these nuclei in the brain get exposed by these exosomes and be taken up by these cells and [or] in the brain. And then those miRNAs can be exposed to follicles to changes and then induce inflammatory changes in the brain.
Norbert Pardi et al. J. Exp Medicine. 2018 Volume 215 No. 6 1571-1588. Juliane Bremer et al., PLoS ONE 2009; 4(9): e7160.
“Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal B cell responses”
“Nucleoside-modified” means that
all the uridines in the mRNA were replaced with 1-methyl-pseudouridine.
This replacement resulted in a robust synthesis of protein
from the mRNA code (protected RNA from degradation)
The result was a very strong antibody
response due to the formation and maintenance of germinal centers in the
spleen.
Another study showed that repeated
exposure to antigen (foreign protein) through immunization resulted in
increased susceptibility to prion protein exposure.
Attributed to an expansion of splenic germinal centers. 26:51.
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