ABSTRACT
The present study was carried out to investigate if ethanol alters the aromatization of androgens and concentrations of hepatic estrogen and androgen receptors. Hepatic aromatization of androgen to estrogen was significantly increased by ethanol administration. There was a significant increase in serum estrogen level but a decreased circulating testosterone level in alcohol-fed rats. Furthermore, the concentration of estrogen receptors in liver cytosol was significantly higher in alcohol-fed rats (37 +/- 5.3 fmol/mg protein), as compared to the intact control value (21 +/- 4.8 fmol/mg protein). However, hepatic androgen receptor levels were much lower (4.4 +/- 0.5) in alcohol-fed rats than those (10.2 +/- 1.4 fmol/mg protein) in control animals. Similarly, castration increased hepatic aromatization of androgens and concentrations of serum estrogen and hepatic estrogen receptors, but it decreased the contents of circulating androgen and hepatic androgen receptors. These findings indicate that alcohol administration is considered a chemical form of castration, altering the hepatic steroid metabolism and sex hormone receptor contents and contributing to the pathogenesis of feminization. A combination of alcohol-feeding and castration has no synergistic effect on the hepatic steroid receptors and aromatization, but this combination does have a more profound effect in lowering the concentration of circulating androgen.
Here are some foods that raise, or increase, your androgen receptors. First, knock off the alcohol except for the occasional celebration of personal milestones. Don't get me wrong. I love red wine. Would drink it regularly if didn't have all the nasty side effects on the brain and liver. Those side effects can make a person irritable and grumpy the next day for which you'll need plenty of coffee the next morning to revive yourself. But alcohol and coffee both deplete your vitamin B stores. In fact, these beverages are referred to as B blockers because they block the absorption of vitamin B into your tissues. Because alcohol does have nasty effects on hormones even tissues, I abstained long ago, decades now. I was always considered a lightweight when friends, relatives, and acquaintances had no problem putting away excessive amounts.
Coffee does have benefits but too much can drain the brain of B vitamins and deplete the pituitary gland [A MAJOR PLAYER IN YOUR ENDOCRINE SYSTEM, sometimes called "the master gland"] hormones.
Which hormones does the pituitary gland make?
The anterior lobe of your pituitary gland makes and releases the following hormones:
Adrenocorticotropic hormone (ACTH or corticotrophin): ACTH plays a role in how your body responds to stress. It stimulates your adrenal glands to produce cortisol (the “stress hormone”), which has many functions, including regulating metabolism, maintaining blood pressure, regulating blood glucose (blood sugar) levels and reducing inflammation, among others.
Follicle-stimulating hormone (FSH): FSH stimulates sperm production in people assigned male at birth. FSH stimulates the ovaries to produce estrogen and plays a role in egg development in people assigned female at birth. This is known as a gonadotrophic hormone.
Growth hormone (GH): In children, growth hormone stimulates growth. In other words, it helps children grow taller. In adults, growth hormone helps maintain healthy muscles and bones and impacts fat distribution. GH also impacts your metabolism (how your body turns the food you eat into energy).
Look at how these idiots describe biological functions. Science is corrupted. F**k these compliant bureaucrats. "assigned"?
Luteinizing hormone (LH): LH stimulates ovulation in people assigned female at birth and testosterone production in people assigned male at birth. LH is also known as a gonadotrophic hormone because of the role it plays in controlling the function of the ovaries and testes, known as the gonads.
Prolactin: Prolactin stimulates breast milk production (lactation) after giving birth. It can affect fertility and sexual functions in adults.
Thyroid-stimulating hormone (TSH): TSH stimulates your thyroid to produce thyroid hormones that manage your metabolism, energy levels, and your nervous system.
And a few more.
But we all want a simplified life. In that case, ignore everything I've said or printed here, and go on about your business. But if you want to maintain a high level of productivity long into your years, then be vigilant on bodily processes that deliver on productivity. To keep your pituitary gland functioning at peak levels as you continue drinking coffee, then it would help, help a lot, to be consuming boron.
The difference between the Pituitary Gland and the Pineal Gland is that the pituitary releases hormones throughout the endocrine system to ensure physiological functions in our body, whereas the pineal gland is mostly responsible for producing melatonin. People take melatonin supplements to keep the pineal gland producing melatonin. Boron helps to keep that organ regulated. Pineal gland is not just for melatonin. It's also responsible for critical thinking. For the Pituitary gland, eat red meat, get sunlight at peak hours, 11-2, get Omega-3s through fish oil, and supplement with vitamin D.
