Showing posts with label Alzheimer's disease. Show all posts
Showing posts with label Alzheimer's disease. Show all posts

Sunday, October 2, 2022

NATTOKINASE DEGRADES AND REDUCES AMYLOID FIBRILS ASSOCIATED WITH ALZHEIMER'S

Monday, November 22, 2021

Want to Treat Gastric Ulcers? Try ZINC CARNOSINE

The world of disease is complicated, unknown, with so many receptors, binding proteins, epithelial cells on membranes that it's quite difficult to make sense of it all.  Sometimes the best we can do is rely on the old standbys, like vitamin D3, vitamin A, vitamin C, vitamin E, zinc, and others to keep ourselves free of pathogens--viruses, bacteria, etc.  And oftentimes the fearmongering around diseases seems interminable.  You find out one thing about a pathogen, and you panic.  Doctors love it when they can cause you to panic when they give you or a loved one a diagnosis of cancer or some other progressive, degenerative, even debilitating disease.  For this reason, medical doctors have lost me.  Recently, I'd learned that the spike proteins that are invading our bodies via the vaccines or transmission of exosomes are recking havoc on our cells and cell membranes, and the quality of our blood.  And given this nightmare, I don't see how folks are still worried about COVID.  COVID seems to be the last of our worries. Was recently reading about prion disease, proteins that cause other proteins to fold and malfunction.  The kinds of conditions caused by prion disease are Parkinson's, Mad Cow Disease, Alzheimer's [I thought this was caused by amyloid plaque], and others.  John Hopkins Medical reports that

A prion is a type of protein that can trigger normal proteins in the brain to fold abnormally. Prion diseases can affect both humans and animals and are sometimes spread to humans by infected meat products. The most common form of prion disease that affects humans is Creutzfeldt-Jakob disease (CJD).

Which is frightening enough.  Science can be fascinating, but if you get a talented scientist placed under the influence of mass murders, like Ralph Baric of North Carolina University, then the world is doomed.

But maybe, just maybe there are some small, insignificant interventions that people can take to either prevent disease or outright cure it into non-existence.  Zinc is one such powerful compound as to elicit respect for what it can do to restore and maintain health.  Here is what PubMed has to say about zinc

Zinc (Zn) is abundantly present in the brain, and accumulates in the synaptic vesicles. Synaptic Zn is released with neuronal excitation, and plays essential roles in learning and memory. Increasing evidence suggests that the disruption of Zn homeostasis is involved in various neurodegenerative diseases including Alzheimer's disease, a vascular type of dementia, and prion diseases. Our and other numerous studies suggest that carnosine (β-alanyl histidine) is protective against these neurodegenerative diseases. Carnosine is an endogenous dipeptide abundantly present in the skeletal muscles and in the brain, and has numerous beneficial effects such as antioxidant, metal chelating, anti-crosslinking, and anti-glycation activities. The complex of carnosine and Zn, termed polaprezinc, is widely used for Zn supplementation therapy and for the treatment of ulcers. Here, we review the link between Zn and these neurodegenerative diseases, and focus on the neuroprotective effects of carnosine. We also discuss the carnosine level in various foodstuffs and beneficial effects of dietary supplementation of carnosine.

The complex of carnosine and Zn, termed polaprezinc sounds interesting.  What is that exactly?  It's Zinc Carnosine, and it's used to heal gastric ulcers.   

Saturday, November 24, 2018

"WHAT MAKES UP THE THINKING BOXES IN OUR SKULL"

from CNET via Drudge Report
Thirty years ago, George Paxinos noticed an unusual assortment of cells lurking near the brain stem--but he didn't think much of it.
Going over the region in 2018, he was once again struck by it. Now Paxinos' new research suggests that the cluster of cells is definitely important. In fact, it appears to be a completely unknown region of the human brain. The early suggestion is that this bundle of neurons may be responsible for fine motor control, dictating our ability to strum the guitar, write and play sports.
Professor Paxinos is one of the world's most respected "brain cartographers". He creates atlases of human and animal brains that allow neuroscientists, brain surgeons and clinicians to get a better grasp of just what makes up the thinking boxes in our skull.
Coming back to the region that he was originally interested in before publishing his first atlas 28 years ago led to the discovery of the tiny grouping of brain cells. He's crowned the new region "the Endorestiform nucleus" because of its location at the base of the brain in the restiform body.
"One intriguing thing about this endorestiform nucleus is that it seems to be present only in the human, we have not been able to detect it in the rhesus monkey or the marmoset that we have studied," he explained.
It's location, between the brain stem and the spinal cord, is the only inkling we currently have about the brain cells function. As Paxinos has been unable to locate the same region in other apes, he guesses that it must be useful in the fine motor control that humans are so uniquely good at.
You can hear professor Paxinos discuss the finding in the video below.

However, while the structure does appear to be important, further work will be required to understand how its function relates to its form. Paxinos only journeys into the brain to craft a map so it will be up to other intrepid brain explorers to journey back to the center of the neural bundle and learn more. 
The oft-repeated line about our brains containing as many neurons as there are stars in the galaxy doesn't quite ring true--but with some 86 billion neurons pulsing away upstairs, improving our understanding of the brain is still a mammoth task. Discoveries like this allow scientists and researchers to understand normal brain physiology, providing great insight on how or why things go wrong in pathologies such as Alzheimer's or motor neuron disease. 
By the way, if you're concerned about the fears of Alzheimer's, be sure to read Bill Sardi's work [herehere, and here] on the one molecule that is poised to eradicate that disease.

Tuesday, May 1, 2018

82-YEAR OLD WOMAN WITH DEMENTIA GETS HER MEMORY BACK AFTER CHANGING DIET

Sylvia also began incorporating other health foods, including broccoli, kale, spinach, sunflower seeds, green tea, oats, sweet potatoes and even dark chocolate with a high percentage of cocoa. All of these foods are known to be beneficial for brain health.

Broccoli, kale, spinach, sunflower seeds, and green tea are heavy mineral chelators, meaning that they prevent overload of iron, calcium, and mercury.  Not only do these foods provide that benefit, but you can get the same benefit from IP6.  See the bottom of this post.  Here is the article from Collective Evolutionh/t Lew Rockwell.
Recently, an 82-year-old woman who suffered from dementia, who couldn’t recognize her own son has miraculously got her memory back after changing her diet.
When his mother’s condition became so severe that for her own safety she had to be kept in the hospital, Mark Hatzer almost came to terms with losing another parent.
Sylvia had lost her memory and parts of her mind, she had even phoned the police once accusing the nurse who was caring for her of kidnap.
A change in diet, which was comprised of high amounts of blueberries and walnuts, has proven to have had a strong impact on Sylvia’s condition that her recipes are now being shared by the Alzheimer’s Society.
Sylvia also began incorporating other health foods, including broccoli, kale, spinach, sunflower seeds, green tea, oats, sweet potatoes and even dark chocolate with a high percentage of cocoa. All of these foods are known to be beneficial for brain health.
Mark and Sylvia devised to diet together after deciding that the medication on its own was not enough, they looked into the research showing that rates of dementia are much lower in Mediterranean countries and copied a lot of their eating habits.
According to Mirror.co.uk
Mark, whose brother Brent also died in 1977, said: “When my mum was in the hospital she thought it was a hotel–but the worst one she had ever been in.
“She didn’t recognize me and phoned the police as she thought she’d been kidnapped.
“Since my dad and brother died we have always been a very close little family unit, just me and my mum, so for her to not know who I was was devastating.
“We were a double act that went everywhere together. I despaired and never felt so alone as I had no other family to turn to.
“Overnight we went from a happy family to one in crisis.
“When she left the hospital, instead of prescribed medication we thought we’d perhaps try an alternative treatment.
“In certain countries, Alzheimer’s is virtually unheard of because of their diet.
“Everyone knows about fish but there is also blueberries, strawberries, Brazil nuts, and walnuts – these are apparently shaped like a brain to give us a sign that they are good for the brain.”
There were also some cognitive exercises that Mark and his mother would do together like jigsaw puzzles crosswords and meeting people in social situations, Sylvia would also exercise by using a pedaling device outfitted for her chair.
Mark said, “It wasn’t an overnight miracle, but after a couple of months she began remembering things like birthdays and was becoming her old self again, more alert, more engaged..
“People think that once you get a diagnosis your life is at an end. You will have good and bad days, but it doesn’t have to be the end. For an 82-year-old she does very well, she looks 10 years younger and if you met her you would not know she had gone through all of this.
“She had to have help with all sorts of things, now she is turning it around. We are living to the older age in this country, but we are not necessarily living healthier."
THE BODY'S ABILITY TO HEAL IS GREATER THAN ANYONE HAS PERMITTED YOU TO BELIEVE
This story just goes to show how resilient our bodies really are if given the right environment. Most of these types of diseases are often related to diet in the first place so that means that they can indeed be reversed with a proper diet. Sure, some of them are genetic and you might be a carrier of the gene, but that is not a guarantee that it will become active, there are things you can do to minimize the risk. Our health is our greatest wealth. We have to realize that we do have a say in our lives and what our fate is.
We have covered the topic before of how aluminum build up in the brain is directly related to dementia and more specifically Alzheimer’s disease, being able to identify this as a cause is important because recognizing this means we can do our part to limit the exposure and to also detoxify our brains and bodies from this damaging heavy metal.
In an article titled, Strong evidence linking Aluminum to Alzheimer’srecently published in The Hippocratic Post website, Exley explained that:
“We already know that the aluminum content of brain tissue in late-onset or sporadic Alzheimer’s disease is significantly higher than is found in age-matched controls. So, individuals who develop Alzheimer’s disease in their late sixties and older also accumulate more aluminum in their brain tissue than individuals of the same age without the disease.
Even higher levels of aluminum have been found in the brains of individuals, diagnosed with an early-onset form of sporadic (usually late onset) Alzheimer’s disease, who have experienced an unusually high exposure to aluminum through the environment (e.g. Camelford) or through their workplace. This means that Alzheimer’s disease has a much earlier age of onset, for example, the fifties or early sixties, in individuals who have been exposed to unusually high levels of aluminum in their everyday lives.”
His most recent study, published by the Journal of Trace Elements in Medicine and Biology in December 2016, titled: Aluminium in brain tissue in familial Alzheimer’s disease, is one of the many studies that he and his team have conducted on the subject of aluminum over the years. However, this study, in particular, is believed to be of significant value, because it is the first time that scientists have measured the level of aluminum in the brain tissue of individuals diagnosed with familial Alzheimer’s disease. (Alzheimer’s disease or AD is considered to be familial if two or more people in a family suffer from the disease.)
According to their paper, the concentrations of aluminum found in brain tissue donated by individuals who died with a diagnosis of familial AD, was the highest level ever measured in human brain tissue.
Professor Exley wrote:
“We now show that some of the highest levels of aluminum ever measured in human brain tissue are found in individuals who have died with a diagnosis of familial Alzheimer’s disease.
The levels of aluminum in brain tissue from individuals with familial Alzheimer’s disease are similar to those recorded in individuals who died of an aluminum-induced encephalopathy while undergoing renal dialysis.”
He explained that:
“Familial Alzheimer’s disease is an early-onset form of the disease with first symptoms occurring as early as 30 or 40 years of age. It is extremely rare, perhaps 2-3% of all cases of Alzheimer’s disease. Its bases are genetic mutations associated with a protein called amyloid-beta, a protein which has been heavily linked with the cause of all forms of Alzheimer’s disease.
Individuals with familial Alzheimer’s disease produce more amyloid beta and the onset of the symptoms of Alzheimer’s disease are much earlier in life.”
THE FIRST STEP TOWARDS CHANGE IS BY RAISING AWARENESS
As more and more awareness grows involving the true causes of these neurodegenerative brain disorders, the more we can do our part to prevent and even treat them and hopefully, eventually eliminate things such as aluminum and other chemicals in our foods to prevent this disease from happening altogether.
Please share this article with anyone you know who knows someone who is suffering from dementia or Alzheimer’s.
Reprinted with permission from Collective Evolution.

Saturday, August 8, 2015

EXCESS TV WATCHING COULD RAISE RISK OF ALZHEIMER'S

Study: Excess TV Watching Could Raise Risk Of Alzheimer’s

This should not come as a surprise.

WASHINGTON (CBSDC) — Too much time in front of the television may contribute to brain damage and a higher risk of developing Alzheimer’s diseasehttp://images.intellitxt.com/ast/adTypes/icon1.png, a new study suggests.

Northern California Institute for Research and Education experts found that four hours of television or more per day can significantly lower cognitive performance in middle age. The study explored the link between sedentary lifestyle, cognitive performance and the risk of developing dementia, as reported by The Washington Post.

The study tracked individuals for 25 years beginning in young adulthood and found that low cognitive test scores were also common among people who reported low levels of physical activityhttp://images.intellitxt.com/ast/adTypes/icon1.png.

Researchers say the findings shed light on important consequences for children and young adults who spend a lot of time in front of screens. However, the research also suggests that people have a choice in changing their lifestyle in order to lower the risk of cognitive decline later in life.

“This is something you can do something about,” Kristine Yaffe, a professor of psychiatry, neurology and epidemiology at the University of California in San Francisco, told the Alzheimer’s Association International Conference in Washington, D.C.

The study examined 3,257 adults between the ages of 18 and 30 years old and investigated the effect television watching and physical activity level had on cognitive performance. The participants answered surveys on their habits three times over the course of 25 years. For the study, researchers defined low physical activity as burning less than 300 calories in 50-minute session three times a week. High television watching was defined as more than four hours a day.

Researchers found that 11 percent were considered heavy TV watchers, 17 percent were considered to have low physical activity, and 3 percent reported both.

Yaffe says those who watched a lot of television were 1.5 percent more likely to perform worse on the cognitive tests when compared to those who watched less. If the participants were relatively inactive and watched a lot of television, they were two times more likely to perform poorly on the tests in midlife, compared to those who were physically activehttp://images.intellitxt.com/ast/adTypes/icon1.png and didn’t watch a lot of television.

“What’s happening at one’s midlife is setting the stage for what’s happening over the next 20 or 30 years,” Yaffe explains, as reported by The Washington Post.

The results highlight the possibility that sedentary habits in early life may have negative impact on dementia risk later in life.