modern methylation cycle epigenetic regulation

Alright folks, step 3 of detox is Methylation. We need to get your liver working optimally and NAC and milk thistle aren’t going to cut it. Over half of us are impacted by epigenetics related to methylation. https://t.co/uq4HPCWeyv

— Anastasis (@OrdersofM) May 24, 2022

Methylation is a complicated process and I will include some links for you to read if you’d like to delve deeper and then give you the supplements and protocol I recommend.

If you only read one thing, read this:  https://t.co/gg2Xtqvpid

— Anastasis (@OrdersofM) May 25, 2022

In my mind, Dr Roberts was the first innovator of modern methylation cycle epigenetic regulation. I love that he has added Dr. Amy Yasko’s work. https://t.co/LTb2tISRF7

This is meaty info that takes time to chew. There is no better place to start a deep dive into the topic.

— Anastasis (@OrdersofM) May 25, 2022

Dr. Roberts explains Methyl Cycle NutriGenomics. 

The Methyl Cycle is the backbone of our physiology.  It's functional status determines our resistance or susceptibility to environmental toxins and microbes.  This is a confusing array of biochemistry, but suffice it to say, a defect at any one point in these interlocking cycles will inevitably affect the  remaining pathways, and your overall health will then suffer.  Methyl Cycle abnormalities explain why you are sick from environmental toxins while the guy next door is just fine, why you are autistic while your fraternal twin brother is not.  While we cannot change your DNA, if we know your weak links we can create "nutritional workarounds" - we can supplement alternative pathways or withhold from your diet molecules that you cannot handle.  If we do not address the Methyl Cycle abnormalities that underlie unexplained or chronic illness - well then the illnesses will remain chronic and unexplained, because it is the Methyl Cycle Abnormalities that predisposed you to ill health.  As antioxidant and detoxification genomic testing is now low in cost, we are extending our attention to variant function in these important systems as well.  the more we know about your genomic weaknesses, the easier it is for you to overcome them.

 

This is a great video series in simple bites.  https://t.co/JXbCUKMJaH

— Anastasis (@OrdersofM) May 25, 2022

Saluti, please find the unroll here: https://t.co/JvemWzKguU See you soon. 🤖

— Thread Reader App (@threadreaderapp) May 25, 2022

How does one accomplish mylenation through food?  Radishes, for one.

What’s so great about this week’s anti-cancer food–plain, pungent radishes?  Let’s talk methylation, for starters.

 

Your DNA is always being damaged, repaired and copied, and methylation, a fundamental biological activity that happens more than a billion times a second, controls that process. Think of your cells as continually engaged in a dance of methylation—adding clusters of carbon and hydrogen atoms (called methyl groups) to DNA and taking them away in order to keep DNA  functioning well. Too little methylation and DNA cannot repair itself, putting you at higher risk of cancer. (But don’t run out and purchase supplements: Too much methylation may also increase your risk.)

What you CAN do to improve methylation is make sure you get enough folate and other B vitamins in your diet. Radishes are a good source of both. (So are dark leafy greens and beans.)

Radishes are also low in calories and carbs as well as crunchy, making them a healthy substitute when you’re craving crackers.

And the clencher? Although they may not resemble their broccoli and cauliflower cousins, radishes are a member of the almighty cruciferous family of vegetables. When it comes to protecting you from cancer, that family is holy! 

Seed oils block protein digestion in the stomach, leading to malnourishment after a full meal, which you see among Americans who overeat; yet lack vital nutrients.

Hello, the unroll you asked for: People love to talk bad about seed oils but not once have a seen… https://t.co/ldDmXbJ7gG Share this if you think it's interesting. 🤖

— Thread Reader App (@threadreaderapp) January 13, 2022

 

I've been told by a doctor fish oil supplements are good for Omega-3 and help inflammation

— Danny (@DMonteban) January 13, 2022

In alphabetical order, these are the seed oils that you want to avoid: Canola oil, Corn oil, Cottonseed oil, Grapeseed oil, Rice bran oil, Safflower oil, Soy oil, and Sunflower oil.  And as you read that list, you might say to yourself, "Wait a minute, isn't Sunflower oil good for you?  I mean it's made from the sun, which is good, right?"  Or what about Rice bran oil?  We've heard so many good things about rice bran, right?  Sort of.  There may be biological benefits derived from some of these seeds in a different form, but in the form of oil due to its processing, it renders them problematic in the biological processes of your body.  

Dr. Catherine Shanahan, otherwise known, as Dr. Cate, writing for Better Nutrition, explains, 

Although they’re usually refined, even unrefined and cold-pressed versions of these oils pose the same health risks, because the oils are naturally rich in polyunsaturated fats (PUFAs). The molecular structure of PUFAs makes them very unstable in the human body, where they generate tremendous amount of free radicals--chaotic reactions that damage cells.  

Free radicals are a normal byproduct of metabolism that our bodies are equipped to handle, but only up to a point. Seed oils produce an onslaught that far exceeds our innate capacity. “Free radicals are bad for us in the same way that radiation is bad for us,” says Dr. Cate. When you eat a lot of PUFA-rich seed oils, she adds, “it’s like you have dirty bombs inside your cells.”

PUFAs are inflammatory and damage the lining of blood vessels, affecting overall circulation and blood flow to the brain, and increasing the risk for heart disease and diabetes.