Showing posts with label Chemosphere. Show all posts
Showing posts with label Chemosphere. Show all posts

Monday, February 2, 2026

MASSIMO: Just 28 days without parabens and phthalates turned off breast cancer genes.

Just 28 days without parabens and phthalates turned off breast cancer genes. Researchers followed a group of healthy women who routinely used common personal-care products containing parabens and phthalates—chemicals found in everything from shampoo and lotion to makeup and fragrance. These compounds can act like estrogen in the body, and excess estrogen-like activity has long been tied to higher breast-cancer risk. For 28 days, 36 women did one simple thing: they switched to paraben- and phthalate-free alternatives. No drugs, no diet changes—just cleaner cosmetics and toiletries. The results were striking: urine tests confirmed that levels of the chemicals’ breakdown products plummeted, proving exposure had been sharply reduced. But the bigger revelation came from breast-tissue biopsies taken before and after the switch. In just four weeks, the women’s breast cells began behaving less like precancerous or cancerous cells. They regained the ability to respond to normal “cell-death” signals (a safeguard tumors often disable). Protective estrogen receptors, which are typically shut down in breast cancer, switched back on. Gene-expression patterns shifted away from high-risk profiles and toward healthier patterns. This is the first human evidence that routine exposure to these everyday chemicals can nudge normal breast cells in a cancer-like direction—and, crucially, that removing the exposure can begin to reverse the process remarkably quickly. It’s not definitive proof that changing your body wash will prevent breast cancer. But it does show that the body notices—and starts to repair itself—almost immediately when you stop putting these substances on your skin.

["Reduction of daily-use parabens and phthalates reverses accumulation of cancer-associated phenotypes within disease-free breast tissue of study subjects," Chemosphere, 2023]