Saturday, January 8, 2022

COUNTERING IMMUNE SENESCENCE

From Life Extension,

As we age, our immune system function deteriorates, leaving us increasingly susceptible to health threats such as cancer, autoimmunity, infections, and chronic inflammation. This process is called immune senescence.

Scientists are studying various methods for countering immune senescence, including young stem-cell mobilized plasma transfusions. Research suggests old blood may contain pro-aging factors whose concentrations are diluted by young-blood transfusions, potentially causing rejuvenating effects.

In addition, several natural interventions, including cistanchereishi, and  zinc may slow or potentially reverse the course of immune senescence.

How Aging Accelerates Immune Decline

Decreased numbers of naïve T cells, or cells that can easily be activated to recognize and respond to diseases like the flu and cancer.

Increased numbers of senescent memory T cells that have lost their ability to divide and function properly and instead release pro-inflammatory molecules.

Decreased natural killer (NK) cell activity, which is linked to increased illness and death from infections, atherosclerosis, and diminished response to the flu vaccine.

Cytomegalovirus infection may be associated with immune senescence, cardiovascular disease, frailty, and mortality. 

Some of the above compounds read like effective anti-aging substances.  Check out what NCBI says about Herba Cistanche,

Herba Cistanche extracts are pharmacologically active, with a range of functions that include improving chronic renal disease and senile constipation, increasing learning/memorizing ability, treating Alzheimer's disease (AD), and improving immunity. 

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