ADVERSE HEALTH OUTCOMES FROM PROLONGED SITTING, LIKE NEGATIVE CARDIOMETABOLIC, I.E., TYPE TWO DIABETES

Who's affected?  Office workers, truck drivers, and others.  

Office workers [truck drivers, couriers, delivery personnel] are exposed to high levels of sedentary time. In addition to cardio-vascular and metabolic health risks, this sedentary time may have musculoskeletal and/or cognitive impacts on office workers.

Cognitive effects of prolonged sitting.  What are they?

low back angle changed towards less lordosis, pelvis movement increased, and mental state deteriorated. 

Metabolic disorders also can result, things like diabetes.  This is serious stuff and not to be trifled with.  

A rapidly increasing body of evidence supports an association between sedentary behaviour and the risk of adverse health outcomes [1]. These include negative cardiometabolic outcomes such as type two diabetes [2], and some cancers [3]. In addition there is epidemiological evidence of increased risk of premature mortality [4,5] and obesity [6] however this is inconclusive.

Prolonged sitting interferes with insulin sensitivity.  

During sitting, muscular passivity increases insulin resistance and influences the transport and oxidation of fatty acids in muscular tissue, and acute exercise is not sufficient to restore all changes. Accordingly, adequate everyday physical activity seems to be important for maintaining the signaling pathways affecting insulin sensitivity.

Musculoskeletal effects of prolonged sitting.  

How does one repair the damage? 

breaks to interrupt prolonged sitting are recommended. 

In other words, get up and walk around.  

HOW TO IMPROVE INSULIN SENSITIVITY?  

Resveratrol to start.  Also, try Butyrate.  

Bill Sardi points out that 

Of note, the combination of leucine + low-dose resveratrol exhibits synergistic action to manage insulin-resistance and obesity in lab animals.[xxxi] 

Polyphenols is one way to go.  Cranberry is one kind. 

Cranberry extract has been found to increase the population of AKK bacteria in lab animals and exert beneficial effects such as reduced insulin resistance and inflammation.[xxvii]

Starch, too, looks like a remedy for waist size.  

In a human study among adults with metabolic syndrome (obesity, insulin resistance) Fibersol-2 reduced waist circumference, belly fat, blood sugar and other measures of metabolic health compared to tea consumption for comparison.[xxxiv]  Among diabetic women, 10 grams of indigestible (resistant) starch reduced insulin, insulin resistance, markers of inflammation (TNF) compared to plain starch.[xxxv]